Complications of patients with hematologic malignancies in a selected Iranian population
Background: Hematologic malignancies in childhood and their treatments can cause dental anomalies and jaw bone abnormalities; therefore, the aim of this study was to assess the prevalence of these disorders in children. Methods: This cross-sectional study was conducted on all children diagnosed with...
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| Format: | Article |
| Language: | English |
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Babol University of Medical Sciences
2023-01-01
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| Series: | Caspian Journal of Internal Medicine |
| Subjects: | |
| Online Access: | http://caspjim.com/article-1-3400-en.html |
| _version_ | 1828068361454485504 |
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| author | Shadbahr Shayeghi mahtab Hamzeh Ahmad Tamaddoni sorayya Khafri farida abesi |
| author_facet | Shadbahr Shayeghi mahtab Hamzeh Ahmad Tamaddoni sorayya Khafri farida abesi |
| author_sort | Shadbahr Shayeghi |
| collection | DOAJ |
| description | Background: Hematologic malignancies in childhood and their treatments can cause dental anomalies and jaw bone abnormalities; therefore, the aim of this study was to assess the prevalence of these disorders in children.
Methods: This cross-sectional study was conducted on all children diagnosed with hematologic malignancies that referred to in Amirkola Children’s Hospital from 2011 to 2018. All of children underwent clinical evaluation in a Dental Radiology Clinic and panoramic imaging was performed. The radiographs were examined for dental anomalies and jaw bone abnormalities. The data were analyzed by descriptive analysis using chi-square, Mann-Whitney and Kruskal-Wallis with a 95% confidence interval.
Results: The study population consisted of 32 children and 9.46% of these patients showed intraoral signs in clinical evaluations. Panoramic radiographs indicated dental anomalies in 12 (63.9%) and jaw bone abnormalities in 17 (89.4%) patients. The most common dental anomaly and bone abnormality were taurodontism and changes in lamina dura, respectively. By measuring the mandibular cortical index (MCI), it was revealed that 13 had osteopenia, in which 4 of them had severe osteopenia (osteoporosis). The statistical analysis demonstrated that there was a significant difference between the incidence of osteoporosis and changes in lamina dura with the gender (p<0.05).
Conclusion: Due to early onset of osteopenia and osteoporosis and the presence of dental and bone abnormalities in half of study population, early assessment of their clinical and radiographic condition can be helpful in the prevention and the early treatment of their oral complications. |
| first_indexed | 2024-04-11T00:00:29Z |
| format | Article |
| id | doaj.art-d6b7dab015fb4d0b8fa5aab552ba4d4b |
| institution | Directory Open Access Journal |
| issn | 2008-6164 2008-6172 |
| language | English |
| last_indexed | 2024-04-11T00:00:29Z |
| publishDate | 2023-01-01 |
| publisher | Babol University of Medical Sciences |
| record_format | Article |
| series | Caspian Journal of Internal Medicine |
| spelling | doaj.art-d6b7dab015fb4d0b8fa5aab552ba4d4b2023-01-10T05:28:09ZengBabol University of Medical SciencesCaspian Journal of Internal Medicine2008-61642008-61722023-01-011411015Complications of patients with hematologic malignancies in a selected Iranian populationShadbahr Shayeghi0mahtab Hamzeh1Ahmad Tamaddoni2sorayya Khafri3farida abesi4 Private Practice, Babol, Iran Private Practice, Babol, Iran Non-Communicable Pediatric Diseases Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran Cancer Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, IR Iran Dental Materials Research Center, Babol University of Medical Sciences, Babol, Iran Background: Hematologic malignancies in childhood and their treatments can cause dental anomalies and jaw bone abnormalities; therefore, the aim of this study was to assess the prevalence of these disorders in children. Methods: This cross-sectional study was conducted on all children diagnosed with hematologic malignancies that referred to in Amirkola Children’s Hospital from 2011 to 2018. All of children underwent clinical evaluation in a Dental Radiology Clinic and panoramic imaging was performed. The radiographs were examined for dental anomalies and jaw bone abnormalities. The data were analyzed by descriptive analysis using chi-square, Mann-Whitney and Kruskal-Wallis with a 95% confidence interval. Results: The study population consisted of 32 children and 9.46% of these patients showed intraoral signs in clinical evaluations. Panoramic radiographs indicated dental anomalies in 12 (63.9%) and jaw bone abnormalities in 17 (89.4%) patients. The most common dental anomaly and bone abnormality were taurodontism and changes in lamina dura, respectively. By measuring the mandibular cortical index (MCI), it was revealed that 13 had osteopenia, in which 4 of them had severe osteopenia (osteoporosis). The statistical analysis demonstrated that there was a significant difference between the incidence of osteoporosis and changes in lamina dura with the gender (p<0.05). Conclusion: Due to early onset of osteopenia and osteoporosis and the presence of dental and bone abnormalities in half of study population, early assessment of their clinical and radiographic condition can be helpful in the prevention and the early treatment of their oral complications.http://caspjim.com/article-1-3400-en.htmlchildhematologic malignanciesradiographyprevalencediagnosis |
| spellingShingle | Shadbahr Shayeghi mahtab Hamzeh Ahmad Tamaddoni sorayya Khafri farida abesi Complications of patients with hematologic malignancies in a selected Iranian population Caspian Journal of Internal Medicine child hematologic malignancies radiography prevalence diagnosis |
| title | Complications of patients with hematologic malignancies in a selected Iranian population |
| title_full | Complications of patients with hematologic malignancies in a selected Iranian population |
| title_fullStr | Complications of patients with hematologic malignancies in a selected Iranian population |
| title_full_unstemmed | Complications of patients with hematologic malignancies in a selected Iranian population |
| title_short | Complications of patients with hematologic malignancies in a selected Iranian population |
| title_sort | complications of patients with hematologic malignancies in a selected iranian population |
| topic | child hematologic malignancies radiography prevalence diagnosis |
| url | http://caspjim.com/article-1-3400-en.html |
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