| Summary: | In this paper, a variety of boundary value problems (BVPs) known as hybrid fractional sequential integro-differential equations (HFSIDs) with two point orders (<inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi mathvariant="fraktur">p</mi><mo>,</mo><mi mathvariant="fraktur">q</mi></mrow></semantics></math></inline-formula>) are investigated. The uniqueness and existence of the solution are discussed via Banach fixed-point theorems. Certain particular theorems associated with Hyers–Ulam and Hyers–Ulam–Rassias stability to the solution, as well as the uniqueness and existence of the solution of the BVPs are studied. The results are illustrated with some particular examples, and the numerical data are analyzed for confirmation of the results. The results obtained in this work are simple and can easily be applicable to physical systems. Furthermore, symmetry analysis of fractional differential equations and HFSIDs are also presented. This is due to the fact that the aforementioned analysis plays a significant role in both the optimization and qualitative theory of fractional differential equations.
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