ELISA based assays to measure adenosine deaminases concentration in serum and saliva for the diagnosis of ADA2 deficiency and cancer

ELISA based assays to measure adenosine deaminases concentration in serum and saliva for the diagnosis of ADA2 deficiency and cancer

Adenosine deaminases (ADAs) are enzymes of purine metabolism converting adenosine to inosine. There are two types of ADAs in humans ADA1 and ADA2. While both ADA1 and ADA2 share the same substrate, they differ in expression, cellular localization, and catalytic properties. The genetic deficiency of...

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Bibliographic Details
Main Authors: Wenwen Luo, Liang Dong, Fenghong Chen, Wenbin Lei, Liya He, Qing Zhou, Thierry Lamy, Andrey V. Zavialov
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Immunology
Subjects:
adenosine deaminase 2
ADA2 deficiency
head and neck cancer
large granular leukocyte leukemia
adenosine deaminase
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.928438/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.928438/full

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