Analysis of vestibular-evoked myogenic potentials in the vestibular migraine
Objectives: The objective of this study is to determine the subclinical vestibular dysfunction of patients with vestibular migraine (VM) in the interattack period who had no vestibular symptoms. We assessed ascending utricular and descending saccular pathways using cervical vestibular-evoked myogeni...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2020-01-01
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| Series: | Neurological Sciences and Neurophysiology |
| Subjects: | |
| Online Access: | http://www.nsnjournal.org/article.asp?issn=2636-865X;year=2020;volume=37;issue=2;spage=63;epage=69;aulast=Tutar |
| _version_ | 1818617989981798400 |
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| author | Belgin Tutar Güler Berkiten Onur Akan Ziya Saltürk Berk Gürpinar Semih Karaketir Tolgar Lütfi Kumral Yavuz Uyar Ömür Biltekin Tuna |
| author_facet | Belgin Tutar Güler Berkiten Onur Akan Ziya Saltürk Berk Gürpinar Semih Karaketir Tolgar Lütfi Kumral Yavuz Uyar Ömür Biltekin Tuna |
| author_sort | Belgin Tutar |
| collection | DOAJ |
| description | Objectives: The objective of this study is to determine the subclinical vestibular dysfunction of patients with vestibular migraine (VM) in the interattack period who had no vestibular symptoms. We assessed ascending utricular and descending saccular pathways using cervical vestibular-evoked myogenic potentials (cVEMP) and ocular vestibular-evoked myogenic potentials (oVEMP) in patients with VM and a healthy control group and then compared the electrophysiologic findings with each other. Materials and Methods: Between January 2017 and January 2018, 116 patients (aged 18–62 years) were enrolled in the study. The study group consisted of 68 women with VM and the control group comprised 48 healthy women. Results: For cVEMP findings, the mean left ear P1 latency of the VM group was statistically significantly longer than that of the control group (P = 0.024; P < 0.05). No statistical significance was found in left ear N1 latency, P1-N1 interpeak intervals and mean amplitudes between the VM and the control groups (P > 0.05). Amplitude asymmetry ratios (AARs) were not statistically significantly different between the two groups in cVEMP (P > 0.05). In terms of oVEMP findings, no statistically significant difference was found in the right ear parameters of N1, P1, P1-N1 intervals, and amplitudes of the VM and the control groups (P > 0.05). The left ear oVEMPs of the VM group showed absent responses in 12 cases and were statistically significant compared with the control group (P = 0.037; P < 0.05). The AARs were significantly greater for the the VM group than the control group in oVEMP (P = 0.006; P < 0.05). Conclusion: These electrophysiologic findings suggest that peripheral vestibular structures such as the utricle, saccule and also other central vestibular structures might be affected in VM. Patients with VM had subclinical vestibular dysfunction despite being in the interattack period. To support the diagnosis of VM, VEMPs are easy and cost-effective tests. |
| first_indexed | 2024-12-16T17:14:28Z |
| format | Article |
| id | doaj.art-d6c964a4b0df4a458712477700d396a5 |
| institution | Directory Open Access Journal |
| issn | 2636-865X |
| language | English |
| last_indexed | 2024-12-16T17:14:28Z |
| publishDate | 2020-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Neurological Sciences and Neurophysiology |
| spelling | doaj.art-d6c964a4b0df4a458712477700d396a52022-12-21T22:23:20ZengWolters Kluwer Medknow PublicationsNeurological Sciences and Neurophysiology2636-865X2020-01-01372636910.4103/NSN.NSN_4_20Analysis of vestibular-evoked myogenic potentials in the vestibular migraineBelgin TutarGüler BerkitenOnur AkanZiya SaltürkBerk GürpinarSemih KaraketirTolgar Lütfi KumralYavuz UyarÖmür Biltekin TunaObjectives: The objective of this study is to determine the subclinical vestibular dysfunction of patients with vestibular migraine (VM) in the interattack period who had no vestibular symptoms. We assessed ascending utricular and descending saccular pathways using cervical vestibular-evoked myogenic potentials (cVEMP) and ocular vestibular-evoked myogenic potentials (oVEMP) in patients with VM and a healthy control group and then compared the electrophysiologic findings with each other. Materials and Methods: Between January 2017 and January 2018, 116 patients (aged 18–62 years) were enrolled in the study. The study group consisted of 68 women with VM and the control group comprised 48 healthy women. Results: For cVEMP findings, the mean left ear P1 latency of the VM group was statistically significantly longer than that of the control group (P = 0.024; P < 0.05). No statistical significance was found in left ear N1 latency, P1-N1 interpeak intervals and mean amplitudes between the VM and the control groups (P > 0.05). Amplitude asymmetry ratios (AARs) were not statistically significantly different between the two groups in cVEMP (P > 0.05). In terms of oVEMP findings, no statistically significant difference was found in the right ear parameters of N1, P1, P1-N1 intervals, and amplitudes of the VM and the control groups (P > 0.05). The left ear oVEMPs of the VM group showed absent responses in 12 cases and were statistically significant compared with the control group (P = 0.037; P < 0.05). The AARs were significantly greater for the the VM group than the control group in oVEMP (P = 0.006; P < 0.05). Conclusion: These electrophysiologic findings suggest that peripheral vestibular structures such as the utricle, saccule and also other central vestibular structures might be affected in VM. Patients with VM had subclinical vestibular dysfunction despite being in the interattack period. To support the diagnosis of VM, VEMPs are easy and cost-effective tests.http://www.nsnjournal.org/article.asp?issn=2636-865X;year=2020;volume=37;issue=2;spage=63;epage=69;aulast=Tutarelectrophysiologyevoked potentialsmigraine |
| spellingShingle | Belgin Tutar Güler Berkiten Onur Akan Ziya Saltürk Berk Gürpinar Semih Karaketir Tolgar Lütfi Kumral Yavuz Uyar Ömür Biltekin Tuna Analysis of vestibular-evoked myogenic potentials in the vestibular migraine Neurological Sciences and Neurophysiology electrophysiology evoked potentials migraine |
| title | Analysis of vestibular-evoked myogenic potentials in the vestibular migraine |
| title_full | Analysis of vestibular-evoked myogenic potentials in the vestibular migraine |
| title_fullStr | Analysis of vestibular-evoked myogenic potentials in the vestibular migraine |
| title_full_unstemmed | Analysis of vestibular-evoked myogenic potentials in the vestibular migraine |
| title_short | Analysis of vestibular-evoked myogenic potentials in the vestibular migraine |
| title_sort | analysis of vestibular evoked myogenic potentials in the vestibular migraine |
| topic | electrophysiology evoked potentials migraine |
| url | http://www.nsnjournal.org/article.asp?issn=2636-865X;year=2020;volume=37;issue=2;spage=63;epage=69;aulast=Tutar |
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