Bilateral secondary testicular, epididymal and spermatic cords carcinoma of prostatic origin: a case report and review of the literature
Abstract Background Prostatic carcinoma is emerging as the most common male malignancy in Nigeria and the second most common male cancer worldwide. Patients often present with locally advances stages, and common sites of metastasis are the spine, pelvis, chest, and long bones. Metastases to the test...
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| Format: | Article |
| Language: | English |
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BMC
2021-05-01
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| Series: | Journal of Medical Case Reports |
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| Online Access: | https://doi.org/10.1186/s13256-021-02807-4 |
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| author | Ifeoluwa S. Olorunsola Amarachukwu C. Etonyeaku Blessing O. Lekwa Olusegun S. Ojo |
| author_facet | Ifeoluwa S. Olorunsola Amarachukwu C. Etonyeaku Blessing O. Lekwa Olusegun S. Ojo |
| author_sort | Ifeoluwa S. Olorunsola |
| collection | DOAJ |
| description | Abstract Background Prostatic carcinoma is emerging as the most common male malignancy in Nigeria and the second most common male cancer worldwide. Patients often present with locally advances stages, and common sites of metastasis are the spine, pelvis, chest, and long bones. Metastases to the testes and spermatic cords are reputed to be rare and may be indicative of a worse outcome, when they occur. We recently encountered a clinical case of bilateral testicular, epididymal and spermatic cords prostatic cancer metastases. Case presentation A 71-year-old Nigerian man, who presented at our hospital with 1-month-old complaints of inability to walk together with low back and bilateral thigh pains. This presentation had been preceded by a 5-month history of lower urinary tract symptoms. On examination, the prostate was hard and nodular as were the left testis and spermatic cord. On histological assessment of a needle biopsy, prostatic adenocarcinoma (Gleason score 5 + 5 = 10) was diagnosed. A subsequent therapeutic bilateral total orchidectomy specimen was found to contain metastatic prostatic carcinoma deposits, in the testes, epididymides, and spermatic cords. Although our patient is currently doing well postoperatively on zoledronic acid, ketoconazole, bicalutamide, and tamsulosin, he is being re-evaluated periodically for any feature of recurrence. Conclusion Since it has implications for eventual outcome, every clinically suspicious therapeutic orchidectomy specimen should be subjected to a detailed histopathological examination in order to exclude secondaries from the primary prostatic malignancy. |
| first_indexed | 2024-12-16T14:32:07Z |
| format | Article |
| id | doaj.art-d6ca12b867dd4902b9425c687bda3c0b |
| institution | Directory Open Access Journal |
| issn | 1752-1947 |
| language | English |
| last_indexed | 2024-12-16T14:32:07Z |
| publishDate | 2021-05-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Medical Case Reports |
| spelling | doaj.art-d6ca12b867dd4902b9425c687bda3c0b2022-12-21T22:28:13ZengBMCJournal of Medical Case Reports1752-19472021-05-011511510.1186/s13256-021-02807-4Bilateral secondary testicular, epididymal and spermatic cords carcinoma of prostatic origin: a case report and review of the literatureIfeoluwa S. Olorunsola0Amarachukwu C. Etonyeaku1Blessing O. Lekwa2Olusegun S. Ojo3Department of Morbid Anatomy and Forensic Medicine, Obafemi Awolowo University Teaching Hospitals Complex (OAUTHC)Department of Surgery, Obafemi Awolowo University Teaching Hospitals ComplexMishmael Hospitals and ClinicsDepartment of Morbid Anatomy and Forensic Medicine, Obafemi Awolowo University Teaching Hospitals Complex (OAUTHC)Abstract Background Prostatic carcinoma is emerging as the most common male malignancy in Nigeria and the second most common male cancer worldwide. Patients often present with locally advances stages, and common sites of metastasis are the spine, pelvis, chest, and long bones. Metastases to the testes and spermatic cords are reputed to be rare and may be indicative of a worse outcome, when they occur. We recently encountered a clinical case of bilateral testicular, epididymal and spermatic cords prostatic cancer metastases. Case presentation A 71-year-old Nigerian man, who presented at our hospital with 1-month-old complaints of inability to walk together with low back and bilateral thigh pains. This presentation had been preceded by a 5-month history of lower urinary tract symptoms. On examination, the prostate was hard and nodular as were the left testis and spermatic cord. On histological assessment of a needle biopsy, prostatic adenocarcinoma (Gleason score 5 + 5 = 10) was diagnosed. A subsequent therapeutic bilateral total orchidectomy specimen was found to contain metastatic prostatic carcinoma deposits, in the testes, epididymides, and spermatic cords. Although our patient is currently doing well postoperatively on zoledronic acid, ketoconazole, bicalutamide, and tamsulosin, he is being re-evaluated periodically for any feature of recurrence. Conclusion Since it has implications for eventual outcome, every clinically suspicious therapeutic orchidectomy specimen should be subjected to a detailed histopathological examination in order to exclude secondaries from the primary prostatic malignancy.https://doi.org/10.1186/s13256-021-02807-4CancerProstateTestesMetastasisOrchidectomy |
| spellingShingle | Ifeoluwa S. Olorunsola Amarachukwu C. Etonyeaku Blessing O. Lekwa Olusegun S. Ojo Bilateral secondary testicular, epididymal and spermatic cords carcinoma of prostatic origin: a case report and review of the literature Journal of Medical Case Reports Cancer Prostate Testes Metastasis Orchidectomy |
| title | Bilateral secondary testicular, epididymal and spermatic cords carcinoma of prostatic origin: a case report and review of the literature |
| title_full | Bilateral secondary testicular, epididymal and spermatic cords carcinoma of prostatic origin: a case report and review of the literature |
| title_fullStr | Bilateral secondary testicular, epididymal and spermatic cords carcinoma of prostatic origin: a case report and review of the literature |
| title_full_unstemmed | Bilateral secondary testicular, epididymal and spermatic cords carcinoma of prostatic origin: a case report and review of the literature |
| title_short | Bilateral secondary testicular, epididymal and spermatic cords carcinoma of prostatic origin: a case report and review of the literature |
| title_sort | bilateral secondary testicular epididymal and spermatic cords carcinoma of prostatic origin a case report and review of the literature |
| topic | Cancer Prostate Testes Metastasis Orchidectomy |
| url | https://doi.org/10.1186/s13256-021-02807-4 |
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