Surprising Structural and Functional Properties of Favism Erythrocytes Are Linked to Special Metabolic Regulation: A Cell Aging Study

Surprising Structural and Functional Properties of Favism Erythrocytes Are Linked to Special Metabolic Regulation: A Cell Aging Study

Favism uniquely arises from a genetic defect of the Glucose-6 Phosphate Dehydrogenase (G6PD) enzyme and results in a severe reduction of erythrocytes’ (RBCs) reducing power that impairs the cells’ ability to respond to oxidative stresses. After exposure to fava beans or a few other drugs, the patien...

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Bibliographic Details
Main Authors:	Simone Dinarelli, Giovanni Longo, Stefka Germanova-Taneva, Svetla Todinova, Sashka Krumova, Marco Girasole
Format:	Article
Language:	English
Published:	MDPI AG 2022-12-01
Series:	International Journal of Molecular Sciences
Subjects:	erythrocytes favism cell aging AFM thermal stability of proteins metabolic adaptation
Online Access:	https://www.mdpi.com/1422-0067/24/1/637

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