Yeast Cellular Stress: Impacts on Bioethanol Production
Bioethanol is the largest biotechnology product and the most dominant biofuel globally. <i>Saccharomyces cerevisiae</i> is the most favored microorganism employed for its industrial production. However, obtaining maximum yields from an ethanol fermentation remains a technical challenge,...
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-11-01
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| Series: | Fermentation |
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| Online Access: | https://www.mdpi.com/2311-5637/6/4/109 |
| _version_ | 1797548009714614272 |
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| author | Joshua Eardley David J. Timson |
| author_facet | Joshua Eardley David J. Timson |
| author_sort | Joshua Eardley |
| collection | DOAJ |
| description | Bioethanol is the largest biotechnology product and the most dominant biofuel globally. <i>Saccharomyces cerevisiae</i> is the most favored microorganism employed for its industrial production. However, obtaining maximum yields from an ethanol fermentation remains a technical challenge, since cellular stresses detrimentally impact on the efficiency of yeast cell growth and metabolism. Ethanol fermentation stresses potentially include osmotic, chaotropic, oxidative, and heat stress, as well as shifts in pH. Well-developed stress responses and tolerance mechanisms make <i>S. cerevisiae</i> industrious, with bioprocessing techniques also being deployed at industrial scale for the optimization of fermentation parameters and the effective management of inhibition issues. Overlap exists between yeast responses to different forms of stress. This review outlines yeast fermentation stresses and known mechanisms conferring stress tolerance, with their further elucidation and improvement possessing the potential to improve fermentation efficiency. |
| first_indexed | 2024-03-10T14:53:16Z |
| format | Article |
| id | doaj.art-d6cb4d8dd32842c990b21d01a18656cc |
| institution | Directory Open Access Journal |
| issn | 2311-5637 |
| language | English |
| last_indexed | 2024-03-10T14:53:16Z |
| publishDate | 2020-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Fermentation |
| spelling | doaj.art-d6cb4d8dd32842c990b21d01a18656cc2023-11-20T20:51:02ZengMDPI AGFermentation2311-56372020-11-016410910.3390/fermentation6040109Yeast Cellular Stress: Impacts on Bioethanol ProductionJoshua Eardley0David J. Timson1School of Pharmacy and Biomolecular Sciences, University of Brighton, Huxley Building, Lewes Road, Brighton BN2 4GJ, UKSchool of Pharmacy and Biomolecular Sciences, University of Brighton, Huxley Building, Lewes Road, Brighton BN2 4GJ, UKBioethanol is the largest biotechnology product and the most dominant biofuel globally. <i>Saccharomyces cerevisiae</i> is the most favored microorganism employed for its industrial production. However, obtaining maximum yields from an ethanol fermentation remains a technical challenge, since cellular stresses detrimentally impact on the efficiency of yeast cell growth and metabolism. Ethanol fermentation stresses potentially include osmotic, chaotropic, oxidative, and heat stress, as well as shifts in pH. Well-developed stress responses and tolerance mechanisms make <i>S. cerevisiae</i> industrious, with bioprocessing techniques also being deployed at industrial scale for the optimization of fermentation parameters and the effective management of inhibition issues. Overlap exists between yeast responses to different forms of stress. This review outlines yeast fermentation stresses and known mechanisms conferring stress tolerance, with their further elucidation and improvement possessing the potential to improve fermentation efficiency.https://www.mdpi.com/2311-5637/6/4/109bioethanolchaotropicityfermentationbiofuel yieldcompatible solutecell stress |
| spellingShingle | Joshua Eardley David J. Timson Yeast Cellular Stress: Impacts on Bioethanol Production Fermentation bioethanol chaotropicity fermentation biofuel yield compatible solute cell stress |
| title | Yeast Cellular Stress: Impacts on Bioethanol Production |
| title_full | Yeast Cellular Stress: Impacts on Bioethanol Production |
| title_fullStr | Yeast Cellular Stress: Impacts on Bioethanol Production |
| title_full_unstemmed | Yeast Cellular Stress: Impacts on Bioethanol Production |
| title_short | Yeast Cellular Stress: Impacts on Bioethanol Production |
| title_sort | yeast cellular stress impacts on bioethanol production |
| topic | bioethanol chaotropicity fermentation biofuel yield compatible solute cell stress |
| url | https://www.mdpi.com/2311-5637/6/4/109 |
| work_keys_str_mv | AT joshuaeardley yeastcellularstressimpactsonbioethanolproduction AT davidjtimson yeastcellularstressimpactsonbioethanolproduction |