Mitogenomics and Evolutionary History of Rodent Whipworms (<i>Trichuris</i> spp.) Originating from Three Biogeographic Regions
<i>Trichuris</i> spp. is a widespread nematode which parasitizes a wide range of mammalian hosts including rodents, the most diverse mammalian order. However, genetic data on rodent whipworms are still scarce, with only one published whole genome (<i>Trichuris muris</i>) desp...
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MDPI AG
2021-06-01
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| Online Access: | https://www.mdpi.com/2075-1729/11/6/540 |
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| author | Jan Petružela Alexis Ribas Joëlle Goüy de Bellocq |
| author_facet | Jan Petružela Alexis Ribas Joëlle Goüy de Bellocq |
| author_sort | Jan Petružela |
| collection | DOAJ |
| description | <i>Trichuris</i> spp. is a widespread nematode which parasitizes a wide range of mammalian hosts including rodents, the most diverse mammalian order. However, genetic data on rodent whipworms are still scarce, with only one published whole genome (<i>Trichuris muris</i>) despite an increasing demand for whole genome data. We sequenced the whipworm mitogenomes from seven rodent hosts belonging to three biogeographic regions (Palearctic, Afrotropical, and Indomalayan), including three previously described species: <i>Trichuris cossoni</i>, <i>Trichuris</i><i>arvicolae,</i> and <i>Trichuris</i><i>mastomysi</i>. We assembled and annotated two complete and five almost complete mitogenomes (lacking only the long non-coding region) and performed comparative genomic and phylogenetic analyses. All the mitogenomes are circular, have the same organisation, and consist of 13 protein-coding, 2 rRNA, and 22 tRNA genes. The phylogenetic analysis supports geographical clustering of whipworm species and indicates that <i>T.</i> <i>mastomysi</i> found in Eastern Africa is able to infect multiple closely related rodent hosts. Our results are informative for species delimitation based on mitochondrial markers and could be further used in studies on phylogeny, phylogeography, and population genetics of rodent whipworms |
| first_indexed | 2024-03-10T10:34:33Z |
| format | Article |
| id | doaj.art-d6cbe8931d184ea59cc5ca78d2de6241 |
| institution | Directory Open Access Journal |
| issn | 2075-1729 |
| language | English |
| last_indexed | 2024-03-10T10:34:33Z |
| publishDate | 2021-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Life |
| spelling | doaj.art-d6cbe8931d184ea59cc5ca78d2de62412023-11-21T23:24:22ZengMDPI AGLife2075-17292021-06-0111654010.3390/life11060540Mitogenomics and Evolutionary History of Rodent Whipworms (<i>Trichuris</i> spp.) Originating from Three Biogeographic RegionsJan Petružela0Alexis Ribas1Joëlle Goüy de Bellocq2Institute of Vertebrate Biology, Czech Academy of Sciences, Květná 8, 603 65 Brno, Czech RepublicSection of Parasitology, Department of Biology, Healthcare and the Environment, Faculty of Pharmacy and Food Sciences, University of Barcelona, 08007 Barcelona, SpainInstitute of Vertebrate Biology, Czech Academy of Sciences, Květná 8, 603 65 Brno, Czech Republic<i>Trichuris</i> spp. is a widespread nematode which parasitizes a wide range of mammalian hosts including rodents, the most diverse mammalian order. However, genetic data on rodent whipworms are still scarce, with only one published whole genome (<i>Trichuris muris</i>) despite an increasing demand for whole genome data. We sequenced the whipworm mitogenomes from seven rodent hosts belonging to three biogeographic regions (Palearctic, Afrotropical, and Indomalayan), including three previously described species: <i>Trichuris cossoni</i>, <i>Trichuris</i><i>arvicolae,</i> and <i>Trichuris</i><i>mastomysi</i>. We assembled and annotated two complete and five almost complete mitogenomes (lacking only the long non-coding region) and performed comparative genomic and phylogenetic analyses. All the mitogenomes are circular, have the same organisation, and consist of 13 protein-coding, 2 rRNA, and 22 tRNA genes. The phylogenetic analysis supports geographical clustering of whipworm species and indicates that <i>T.</i> <i>mastomysi</i> found in Eastern Africa is able to infect multiple closely related rodent hosts. Our results are informative for species delimitation based on mitochondrial markers and could be further used in studies on phylogeny, phylogeography, and population genetics of rodent whipwormshttps://www.mdpi.com/2075-1729/11/6/540<i>Trichuris</i>whipwormsmitogenomescomparative genomicsrodentspalearctic |
| spellingShingle | Jan Petružela Alexis Ribas Joëlle Goüy de Bellocq Mitogenomics and Evolutionary History of Rodent Whipworms (<i>Trichuris</i> spp.) Originating from Three Biogeographic Regions Life <i>Trichuris</i> whipworms mitogenomes comparative genomics rodents palearctic |
| title | Mitogenomics and Evolutionary History of Rodent Whipworms (<i>Trichuris</i> spp.) Originating from Three Biogeographic Regions |
| title_full | Mitogenomics and Evolutionary History of Rodent Whipworms (<i>Trichuris</i> spp.) Originating from Three Biogeographic Regions |
| title_fullStr | Mitogenomics and Evolutionary History of Rodent Whipworms (<i>Trichuris</i> spp.) Originating from Three Biogeographic Regions |
| title_full_unstemmed | Mitogenomics and Evolutionary History of Rodent Whipworms (<i>Trichuris</i> spp.) Originating from Three Biogeographic Regions |
| title_short | Mitogenomics and Evolutionary History of Rodent Whipworms (<i>Trichuris</i> spp.) Originating from Three Biogeographic Regions |
| title_sort | mitogenomics and evolutionary history of rodent whipworms i trichuris i spp originating from three biogeographic regions |
| topic | <i>Trichuris</i> whipworms mitogenomes comparative genomics rodents palearctic |
| url | https://www.mdpi.com/2075-1729/11/6/540 |
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