Regression modelling of conditional morphogene expression links and quantifies the impact of growth rate, fitness and macromorphology with protein secretion in Aspergillus niger

Regression modelling of conditional morphogene expression links and quantifies the impact of growth rate, fitness and macromorphology with protein secretion in Aspergillus niger

Abstract Background Filamentous fungi are used as industrial cell factories to produce a diverse portfolio of proteins, organic acids, and secondary metabolites in submerged fermentation. Generating optimized strains for maximum product titres relies on a complex interplay of molecular, cellular, mo...

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Bibliographic Details
Main Authors: Timothy C. Cairns, Tom de Kanter, Xiaomei Z. Zheng, Ping Zheng, Jibin Sun, Vera Meyer
Format: Article
Language:English
Published: BMC 2023-06-01
Series:Biotechnology for Biofuels and Bioproducts
Subjects:
Aspergillus niger
Macromorphology
Pellet
Cell wall
Chitin
Growth rate
Online Access:https://doi.org/10.1186/s13068-023-02345-9

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