Endoluminal Vacuum Therapy for Iatrogenic Perforation of the Proximal Esophagus—Case Report of a Patient with Esophageal Involvement in Pemphigus Vulgaris

Pemphigus vulgaris (PV) is a rare autoimmune disease affecting the skin and mucous membranes. Recent studies have shown a relatively high incidence of esophageal involvement in PV. To distinguish between the esophageal involvement of PV and other pathologies, early endoscopic evaluation is essential...

Full description

Bibliographic Details
Main Authors: Sabine Wächter, Leif Schiffmann, Ulrike W. Denzer
Format: Article
Language:English
Published: Thieme Medical and Scientific Publishers Pvt. Ltd. 2020-12-01
Series:Journal of Digestive Endoscopy
Subjects:
Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/s-0040-1716629
Description
Summary:Pemphigus vulgaris (PV) is a rare autoimmune disease affecting the skin and mucous membranes. Recent studies have shown a relatively high incidence of esophageal involvement in PV. To distinguish between the esophageal involvement of PV and other pathologies, early endoscopic evaluation is essential to obtain tissue for histological analysis. Here, we present the first case of endoluminal vacuum therapy (EVT) for a patient with esophageal involvement in PV and with associated iatrogenic perforation of the proximal esophagus. In comparison to classical treatment options for perforations of the proximal esophagus consisting of either stent insertion or surgical intervention, EVT seems to be a promising alternative with a good clinical outcome.
ISSN:0976-5042
0976-5050