Aplasia Cutis Congenita in a Newborn of Diabetic Mother: A Case Report and Review of Literature
Background: Aplasia cutis congenita (ACC) is a rare condition regarded as a congenital absence of the epidermis, dermis, and in some cases, subcutaneous tissues in the newborn. The pathogenic mechanism is unclear, although the condition has been described as a result of the disrupted development or...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Mazandaran University of Medical Sciences
2023-07-01
|
| Series: | Journal of Pediatrics Review |
| Subjects: | |
| Online Access: | http://jpr.mazums.ac.ir/article-1-522-en.pdf |
| _version_ | 1797689075757481984 |
|---|---|
| author | Hajar Pasha Alireza Yahyaei Shahandashti Fatemeh Haghshenas Amir Bahari Bandari |
| author_facet | Hajar Pasha Alireza Yahyaei Shahandashti Fatemeh Haghshenas Amir Bahari Bandari |
| author_sort | Hajar Pasha |
| collection | DOAJ |
| description | Background: Aplasia cutis congenita (ACC) is a rare condition regarded as a congenital absence of the epidermis, dermis, and in some cases, subcutaneous tissues in the newborn. The pathogenic mechanism is unclear, although the condition has been described as a result of the disrupted development or degeneration of skin in utero. ACC may be observed with fetus papyraceous (FP).
Case Presentation: We report a case of an 8-hour-old newborn female with bilateral symmetrically distributed, stellate type of truncal ACC at birth. She was the survivor twin as the other fetus died at 13wk+3d gestation. This condition describes ACC with FP. Physical examination showed otherwise normal and managed with no other congenital abnormalities. The newborn was treated with antibacterial ointment and antibiotics, and lesions resolved spontaneously within 5 days, leaving scars.
Conclusions: This report explained a newborn with type V cutis aplasia congentia in whom the detection was approved based on the revision of antenatal history and clinical features. The protocol outcome revealed that the topical and systemic antibiotic and washing with normal saline could be an effective treatment for the healing of ACC lesions. Follow-up after 3 months indicated that the skin lesion completely healed, leaving a very small atrophic scar, and no further lesion management was required. |
| first_indexed | 2024-03-12T01:40:42Z |
| format | Article |
| id | doaj.art-d6cefcb113ea40e59089411bdff537cc |
| institution | Directory Open Access Journal |
| issn | 2322-4398 2322-4401 |
| language | English |
| last_indexed | 2024-03-12T01:40:42Z |
| publishDate | 2023-07-01 |
| publisher | Mazandaran University of Medical Sciences |
| record_format | Article |
| series | Journal of Pediatrics Review |
| spelling | doaj.art-d6cefcb113ea40e59089411bdff537cc2023-09-10T12:31:14ZengMazandaran University of Medical SciencesJournal of Pediatrics Review2322-43982322-44012023-07-01113261266Aplasia Cutis Congenita in a Newborn of Diabetic Mother: A Case Report and Review of LiteratureHajar Pasha0Alireza Yahyaei Shahandashti1Fatemeh Haghshenas2Amir Bahari Bandari3 Social Determinants of Health Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran. Neonate Department of Imam Ali (AS), Mzandaran University of Medical Sciences, Amol, Iran. Neonate Department of Imam Ali (AS), Mzandaran University of Medical Sciences, Amol, Iran. Neonate Department of Imam Ali (AS), Mzandaran University of Medical Sciences, Amol, Iran. Background: Aplasia cutis congenita (ACC) is a rare condition regarded as a congenital absence of the epidermis, dermis, and in some cases, subcutaneous tissues in the newborn. The pathogenic mechanism is unclear, although the condition has been described as a result of the disrupted development or degeneration of skin in utero. ACC may be observed with fetus papyraceous (FP). Case Presentation: We report a case of an 8-hour-old newborn female with bilateral symmetrically distributed, stellate type of truncal ACC at birth. She was the survivor twin as the other fetus died at 13wk+3d gestation. This condition describes ACC with FP. Physical examination showed otherwise normal and managed with no other congenital abnormalities. The newborn was treated with antibacterial ointment and antibiotics, and lesions resolved spontaneously within 5 days, leaving scars. Conclusions: This report explained a newborn with type V cutis aplasia congentia in whom the detection was approved based on the revision of antenatal history and clinical features. The protocol outcome revealed that the topical and systemic antibiotic and washing with normal saline could be an effective treatment for the healing of ACC lesions. Follow-up after 3 months indicated that the skin lesion completely healed, leaving a very small atrophic scar, and no further lesion management was required.http://jpr.mazums.ac.ir/article-1-522-en.pdfaplasia cutis congenitanewbornskin diseases |
| spellingShingle | Hajar Pasha Alireza Yahyaei Shahandashti Fatemeh Haghshenas Amir Bahari Bandari Aplasia Cutis Congenita in a Newborn of Diabetic Mother: A Case Report and Review of Literature Journal of Pediatrics Review aplasia cutis congenita newborn skin diseases |
| title | Aplasia Cutis Congenita in a Newborn of Diabetic Mother: A Case Report and Review of Literature |
| title_full | Aplasia Cutis Congenita in a Newborn of Diabetic Mother: A Case Report and Review of Literature |
| title_fullStr | Aplasia Cutis Congenita in a Newborn of Diabetic Mother: A Case Report and Review of Literature |
| title_full_unstemmed | Aplasia Cutis Congenita in a Newborn of Diabetic Mother: A Case Report and Review of Literature |
| title_short | Aplasia Cutis Congenita in a Newborn of Diabetic Mother: A Case Report and Review of Literature |
| title_sort | aplasia cutis congenita in a newborn of diabetic mother a case report and review of literature |
| topic | aplasia cutis congenita newborn skin diseases |
| url | http://jpr.mazums.ac.ir/article-1-522-en.pdf |
| work_keys_str_mv | AT hajarpasha aplasiacutiscongenitainanewbornofdiabeticmotheracasereportandreviewofliterature AT alirezayahyaeishahandashti aplasiacutiscongenitainanewbornofdiabeticmotheracasereportandreviewofliterature AT fatemehhaghshenas aplasiacutiscongenitainanewbornofdiabeticmotheracasereportandreviewofliterature AT amirbaharibandari aplasiacutiscongenitainanewbornofdiabeticmotheracasereportandreviewofliterature |