Many ribosomal protein genes are cancer genes in zebrafish.
We have generated several hundred lines of zebrafish (Danio rerio), each heterozygous for a recessive embryonic lethal mutation. Since many tumor suppressor genes are recessive lethals, we screened our colony for lines that display early mortality and/or gross evidence of tumors. We identified 12 li...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2004-05-01
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| Series: | PLoS Biology |
| Online Access: | http://europepmc.org/articles/PMC406397?pdf=render |