Xanthogranulomatous prostatitis: a mimic of carcinoma of prostate

<p>Abstract</p> <p>Background</p> <p>Xanthogranulomatous prostatitis is an unusual benign inflammatory process of prostate. Clinically it mimics prostatic carcinoma, requiring pathological examination for diagnosis.</p> <p>Case presentation</p> <p&g...

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Main Authors: Rafique Muhammad, Yaqoob Nausheen
Format: Article
Language:English
Published: BMC 2006-06-01
Series:World Journal of Surgical Oncology
Online Access:http://www.wjso.com/content/4/1/30
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author Rafique Muhammad
Yaqoob Nausheen
author_facet Rafique Muhammad
Yaqoob Nausheen
author_sort Rafique Muhammad
collection DOAJ
description <p>Abstract</p> <p>Background</p> <p>Xanthogranulomatous prostatitis is an unusual benign inflammatory process of prostate. Clinically it mimics prostatic carcinoma, requiring pathological examination for diagnosis.</p> <p>Case presentation</p> <p>A 60-year-old patient presented with 6 months history of increasing difficulty in micturition. On digital rectal examination prostate was hard and nodular and estimated weight was 50-gram. His serum prostate specific antigen (PSA) was 150 ng/ml. Clinically a locally advanced carcinoma of prostate was suspected. In view of severe obstructive urinary symptoms and significant post-micturition residual urine, transurethral resection of prostate was carried out. Histopathological examination of resected prostatic tissue revealed xanthogranulomatous prostatitis with no evidence of malignancy. Patient remains symptom free at 16 months follow-up and serum PSA has decreased to 6 ng/ml.</p> <p>Conclusion</p> <p>Xanthogranulomatous prostatitis is a benign inflammatory disorder of prostate that can clinically and even biochemically mimic prostatic carcinoma. A high degree of suspecion and close co-operation with pathologist is necessary for the diagnosis of xanthogranulomatous prostatitis.</p>
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spelling doaj.art-d6ded9ef91ec4572b70aaba854ba85862022-12-21T21:20:47ZengBMCWorld Journal of Surgical Oncology1477-78192006-06-01413010.1186/1477-7819-4-30Xanthogranulomatous prostatitis: a mimic of carcinoma of prostateRafique MuhammadYaqoob Nausheen<p>Abstract</p> <p>Background</p> <p>Xanthogranulomatous prostatitis is an unusual benign inflammatory process of prostate. Clinically it mimics prostatic carcinoma, requiring pathological examination for diagnosis.</p> <p>Case presentation</p> <p>A 60-year-old patient presented with 6 months history of increasing difficulty in micturition. On digital rectal examination prostate was hard and nodular and estimated weight was 50-gram. His serum prostate specific antigen (PSA) was 150 ng/ml. Clinically a locally advanced carcinoma of prostate was suspected. In view of severe obstructive urinary symptoms and significant post-micturition residual urine, transurethral resection of prostate was carried out. Histopathological examination of resected prostatic tissue revealed xanthogranulomatous prostatitis with no evidence of malignancy. Patient remains symptom free at 16 months follow-up and serum PSA has decreased to 6 ng/ml.</p> <p>Conclusion</p> <p>Xanthogranulomatous prostatitis is a benign inflammatory disorder of prostate that can clinically and even biochemically mimic prostatic carcinoma. A high degree of suspecion and close co-operation with pathologist is necessary for the diagnosis of xanthogranulomatous prostatitis.</p>http://www.wjso.com/content/4/1/30
spellingShingle Rafique Muhammad
Yaqoob Nausheen
Xanthogranulomatous prostatitis: a mimic of carcinoma of prostate
World Journal of Surgical Oncology
title Xanthogranulomatous prostatitis: a mimic of carcinoma of prostate
title_full Xanthogranulomatous prostatitis: a mimic of carcinoma of prostate
title_fullStr Xanthogranulomatous prostatitis: a mimic of carcinoma of prostate
title_full_unstemmed Xanthogranulomatous prostatitis: a mimic of carcinoma of prostate
title_short Xanthogranulomatous prostatitis: a mimic of carcinoma of prostate
title_sort xanthogranulomatous prostatitis a mimic of carcinoma of prostate
url http://www.wjso.com/content/4/1/30
work_keys_str_mv AT rafiquemuhammad xanthogranulomatousprostatitisamimicofcarcinomaofprostate
AT yaqoobnausheen xanthogranulomatousprostatitisamimicofcarcinomaofprostate