Integrative analysis of copy number and gene expression in breast cancer using formalin-fixed paraffin-embedded core biopsy tissue: a feasibility study

Integrative analysis of copy number and gene expression in breast cancer using formalin-fixed paraffin-embedded core biopsy tissue: a feasibility study

Abstract Background An absence of reliable molecular markers has hampered individualised breast cancer treatments, and a major limitation for translational research is the lack of fresh tissue. There are, however, abundant banks of formalin-fixed paraffin-embedded (FFPE) tissue. This study evaluated...

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Bibliographic Details
Main Authors: Mahesh Iddawela, Oscar Rueda, Jenny Eremin, Oleg Eremin, Jed Cowley, Helena M. Earl, Carlos Caldas
Format: Article
Language:English
Published: BMC 2017-07-01
Series:BMC Genomics
Subjects:
Gene Expression
Copy Number
FFPE
Genomics
Breast Cancer
DASL
Online Access:http://link.springer.com/article/10.1186/s12864-017-3867-3

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