Post-liver transplantation immonusuppression: main principles and modern implementation
Liver transplantation is the only radical treatment option for the patients with end-stage liver disease. Immunosuppressive therapy is essential for survival of the liver graft and the recipient. There are several tactics of immunosuppression, majority of them utilising tacrolimus as the mainstay. P...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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National Scientific Medical Center
2018-09-01
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| Series: | Ķazaķstannyṇ Klinikalyķ Medicinasy |
| Subjects: | |
| Online Access: | https://www.clinmedkaz.org/download/post-liver-transplantation-immonusuppression-main-principles-and-modern-implementation-9022.pdf |
| _version_ | 1818491244090753024 |
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| author | Kakharman Yesmembetov Kulpash Kaliaskarova Zhanat Spatayev |
| author_facet | Kakharman Yesmembetov Kulpash Kaliaskarova Zhanat Spatayev |
| author_sort | Kakharman Yesmembetov |
| collection | DOAJ |
| description | Liver transplantation is the only radical treatment option for the patients with end-stage liver disease. Immunosuppressive therapy is essential for survival of the liver graft and the recipient. There are several tactics of immunosuppression, majority of them utilising tacrolimus as the mainstay. Prolonged use of immunosuppressive drugs is associated with serious adverse effects. Thus, majority of the transplant-centers use combination of several immunosuppressive agents in order to minimise risk and effects of adverse events. |
| first_indexed | 2024-12-10T17:28:12Z |
| format | Article |
| id | doaj.art-d6e0ca9b79854e73baea2e6ebc2589ef |
| institution | Directory Open Access Journal |
| issn | 1812-2892 2313-1519 |
| language | English |
| last_indexed | 2024-12-10T17:28:12Z |
| publishDate | 2018-09-01 |
| publisher | National Scientific Medical Center |
| record_format | Article |
| series | Ķazaķstannyṇ Klinikalyķ Medicinasy |
| spelling | doaj.art-d6e0ca9b79854e73baea2e6ebc2589ef2022-12-22T01:39:46ZengNational Scientific Medical CenterĶazaķstannyṇ Klinikalyķ Medicinasy1812-28922313-15192018-09-0134961410.23950/1812-2892-JCMK-00340Post-liver transplantation immonusuppression: main principles and modern implementationKakharman Yesmembetov0Kulpash Kaliaskarova1Zhanat Spatayev2Department of Hepatology, Republican Diagnostic Сenter, University Medical Center, Astana, Republic of KazakhstanDepartment of Hepatology, Republican Diagnostic Сenter, University Medical Center, Astana, Republic of KazakhstanDepartment of Hepatobiliary Surgery and Liver Transplantation, National Scientific Center for Oncology and Transplantology, University Medical Center, Astana, Republic of KazakhstanLiver transplantation is the only radical treatment option for the patients with end-stage liver disease. Immunosuppressive therapy is essential for survival of the liver graft and the recipient. There are several tactics of immunosuppression, majority of them utilising tacrolimus as the mainstay. Prolonged use of immunosuppressive drugs is associated with serious adverse effects. Thus, majority of the transplant-centers use combination of several immunosuppressive agents in order to minimise risk and effects of adverse events.https://www.clinmedkaz.org/download/post-liver-transplantation-immonusuppression-main-principles-and-modern-implementation-9022.pdfliver transplantationimmunosuppressionliver cirrhosistacrolimusmycophenolic acid |
| spellingShingle | Kakharman Yesmembetov Kulpash Kaliaskarova Zhanat Spatayev Post-liver transplantation immonusuppression: main principles and modern implementation Ķazaķstannyṇ Klinikalyķ Medicinasy liver transplantation immunosuppression liver cirrhosis tacrolimus mycophenolic acid |
| title | Post-liver transplantation immonusuppression: main principles and modern implementation |
| title_full | Post-liver transplantation immonusuppression: main principles and modern implementation |
| title_fullStr | Post-liver transplantation immonusuppression: main principles and modern implementation |
| title_full_unstemmed | Post-liver transplantation immonusuppression: main principles and modern implementation |
| title_short | Post-liver transplantation immonusuppression: main principles and modern implementation |
| title_sort | post liver transplantation immonusuppression main principles and modern implementation |
| topic | liver transplantation immunosuppression liver cirrhosis tacrolimus mycophenolic acid |
| url | https://www.clinmedkaz.org/download/post-liver-transplantation-immonusuppression-main-principles-and-modern-implementation-9022.pdf |
| work_keys_str_mv | AT kakharmanyesmembetov postlivertransplantationimmonusuppressionmainprinciplesandmodernimplementation AT kulpashkaliaskarova postlivertransplantationimmonusuppressionmainprinciplesandmodernimplementation AT zhanatspatayev postlivertransplantationimmonusuppressionmainprinciplesandmodernimplementation |