Detection of Pathognomonic Biomarker PrP<sup>Sc</sup> and the Contribution of Cell Free-Amplification Techniques to the Diagnosis of Prion Diseases

Detection of Pathognomonic Biomarker PrP<sup>Sc</sup> and the Contribution of Cell Free-Amplification Techniques to the Diagnosis of Prion Diseases

Transmissible spongiform encephalopathies or prion diseases are rapidly progressive neurodegenerative diseases, the clinical manifestation of which can resemble other promptly evolving neurological maladies. Therefore, the unequivocal ante-mortem diagnosis is highly challenging and was only possible...

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Bibliographic Details
Main Authors: Hasier Eraña, Jorge M. Charco, Ezequiel González-Miranda, Sandra García-Martínez, Rafael López-Moreno, Miguel A. Pérez-Castro, Carlos M. Díaz-Domínguez, Adrián García-Salvador, Joaquín Castilla
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Biomolecules
Subjects:
transmissible spongiform encephalopathy
prion disease
prp<sup>sc</sup>
diagnostic
pmca
rt-quic
Online Access:https://www.mdpi.com/2218-273X/10/3/469

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