Establishment and characterization of patient-derived head and neck cancer models from surgical specimens and endoscopic biopsies
Abstract Background Head and neck squamous cell carcinoma (HNSCC) is heterogeneous in etiology, phenotype and biology. Patient-derived xenografts (PDX) maintain morphology and molecular profiling of the original tumors and have become a standard “Avatar” model for human cancer research. However, res...
Main Authors: | , , , , , , , , , , , , , , |
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格式: | 文件 |
语言: | English |
出版: |
BMC
2021-08-01
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丛编: | Journal of Experimental & Clinical Cancer Research |
主题: | |
在线阅读: | https://doi.org/10.1186/s13046-021-02047-w |