Seroprevalence and Risk Factors for Human Herpesvirus 8 Infection, Rural Egypt
To determine whether human herpesvirus 8 (HHV-8) is associated with schistosomal and hepatitis C virus infections in Egypt, we surveyed 965 rural household participants who had been tested for HHV-8 and schistosomal infection (seroprevalence 14.2% and 68.6%, respectively, among those <15 years of...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Centers for Disease Control and Prevention
2008-04-01
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| Series: | Emerging Infectious Diseases |
| Subjects: | |
| Online Access: | https://wwwnc.cdc.gov/eid/article/14/4/07-0935_article |
| _version_ | 1819158531191865344 |
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| author | Sam M. Mbulaiteye Ruth M. Pfeiffer Bryan Dolan Victor C.W. Tsang John Noh Nabiel N.H. Mikhail Mohamed Abdel-Hamid Mohamed Hashem Denise Whitby G. Thomas Strickland James J. Goedert |
| author_facet | Sam M. Mbulaiteye Ruth M. Pfeiffer Bryan Dolan Victor C.W. Tsang John Noh Nabiel N.H. Mikhail Mohamed Abdel-Hamid Mohamed Hashem Denise Whitby G. Thomas Strickland James J. Goedert |
| author_sort | Sam M. Mbulaiteye |
| collection | DOAJ |
| description | To determine whether human herpesvirus 8 (HHV-8) is associated with schistosomal and hepatitis C virus infections in Egypt, we surveyed 965 rural household participants who had been tested for HHV-8 and schistosomal infection (seroprevalence 14.2% and 68.6%, respectively, among those <15 years of age, and 24.2% and 72.8%, respectively, among those ≥15 years of age). Among adults, HHV-8 seropositivity was associated with higher age, lower education, dental treatment, tattoos, >10 lifetime injections, and hepatitis C virus seropositivity. In adjusted analyses, HHV-8 seropositivity was associated with dental treatment among men (odds ratio [OR] 2.4, 95% confidence interval [CI] 1.1–5.2) and hepatitis C virus seropositivity among women (OR 3.3, 95% CI 1.4–7.9). HHV-8 association with antischistosomal antibodies was not significant for men (OR 2.1, 95% CI 0.3–16.4), but marginal for women (OR 1.5, 95% CI 1.0–2.5). Our findings suggest salivary and possible nosocomial HHV-8 transmission in rural Egypt. |
| first_indexed | 2024-12-22T16:26:04Z |
| format | Article |
| id | doaj.art-d6e6f1c0db304080bd7f7b369a072c78 |
| institution | Directory Open Access Journal |
| issn | 1080-6040 1080-6059 |
| language | English |
| last_indexed | 2024-12-22T16:26:04Z |
| publishDate | 2008-04-01 |
| publisher | Centers for Disease Control and Prevention |
| record_format | Article |
| series | Emerging Infectious Diseases |
| spelling | doaj.art-d6e6f1c0db304080bd7f7b369a072c782022-12-21T18:20:10ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592008-04-0114458659110.3201/eid1404.070935Seroprevalence and Risk Factors for Human Herpesvirus 8 Infection, Rural EgyptSam M. MbulaiteyeRuth M. PfeifferBryan DolanVictor C.W. TsangJohn NohNabiel N.H. MikhailMohamed Abdel-HamidMohamed HashemDenise WhitbyG. Thomas StricklandJames J. GoedertTo determine whether human herpesvirus 8 (HHV-8) is associated with schistosomal and hepatitis C virus infections in Egypt, we surveyed 965 rural household participants who had been tested for HHV-8 and schistosomal infection (seroprevalence 14.2% and 68.6%, respectively, among those <15 years of age, and 24.2% and 72.8%, respectively, among those ≥15 years of age). Among adults, HHV-8 seropositivity was associated with higher age, lower education, dental treatment, tattoos, >10 lifetime injections, and hepatitis C virus seropositivity. In adjusted analyses, HHV-8 seropositivity was associated with dental treatment among men (odds ratio [OR] 2.4, 95% confidence interval [CI] 1.1–5.2) and hepatitis C virus seropositivity among women (OR 3.3, 95% CI 1.4–7.9). HHV-8 association with antischistosomal antibodies was not significant for men (OR 2.1, 95% CI 0.3–16.4), but marginal for women (OR 1.5, 95% CI 1.0–2.5). Our findings suggest salivary and possible nosocomial HHV-8 transmission in rural Egypt.https://wwwnc.cdc.gov/eid/article/14/4/07-0935_articleHHV-8epidemiologytransmissionAfricacancerschistosomiasis |
| spellingShingle | Sam M. Mbulaiteye Ruth M. Pfeiffer Bryan Dolan Victor C.W. Tsang John Noh Nabiel N.H. Mikhail Mohamed Abdel-Hamid Mohamed Hashem Denise Whitby G. Thomas Strickland James J. Goedert Seroprevalence and Risk Factors for Human Herpesvirus 8 Infection, Rural Egypt Emerging Infectious Diseases HHV-8 epidemiology transmission Africa cancer schistosomiasis |
| title | Seroprevalence and Risk Factors for Human Herpesvirus 8 Infection, Rural Egypt |
| title_full | Seroprevalence and Risk Factors for Human Herpesvirus 8 Infection, Rural Egypt |
| title_fullStr | Seroprevalence and Risk Factors for Human Herpesvirus 8 Infection, Rural Egypt |
| title_full_unstemmed | Seroprevalence and Risk Factors for Human Herpesvirus 8 Infection, Rural Egypt |
| title_short | Seroprevalence and Risk Factors for Human Herpesvirus 8 Infection, Rural Egypt |
| title_sort | seroprevalence and risk factors for human herpesvirus 8 infection rural egypt |
| topic | HHV-8 epidemiology transmission Africa cancer schistosomiasis |
| url | https://wwwnc.cdc.gov/eid/article/14/4/07-0935_article |
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