Risk Factors for Prolonged Mechanical Ventilation and Delayed Extubation Following Bimaxillary Orthognathic Surgery: A Single-Center Retrospective Cohort Study
Background: Bimaxillary orthognathic surgery bears the risk of severe postoperative airway complications. There are no clear recommendations for immediate postoperative follow-up and monitoring. Objective: to identify potential risk factors for prolonged mechanical ventilation and delayed extubation...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-07-01
|
| Series: | Journal of Clinical Medicine |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2077-0383/11/13/3829 |
| _version_ | 1797434184503918592 |
|---|---|
| author | Christian I. Schwer Teresa Roth Mathieu Gass René Rothweiler Torsten Loop Marc C. Metzger Johannes Kalbhenn |
| author_facet | Christian I. Schwer Teresa Roth Mathieu Gass René Rothweiler Torsten Loop Marc C. Metzger Johannes Kalbhenn |
| author_sort | Christian I. Schwer |
| collection | DOAJ |
| description | Background: Bimaxillary orthognathic surgery bears the risk of severe postoperative airway complications. There are no clear recommendations for immediate postoperative follow-up and monitoring. Objective: to identify potential risk factors for prolonged mechanical ventilation and delayed extubation in patients undergoing bimaxillary orthognathic surgery. Methods: The data of all consecutive patients undergoing bimaxillary surgery between May 2012 and October 2019 were analyzed in a single-center retrospective cohort study. The clinical data were evaluated regarding baseline characteristics and potential factors linked with delayed extubation. Results: A total of 195 patients were included; 54.9% were female, and the median age was 23 years (IQR 5). The median body mass index was 23.1 (IQR 8). Nine patients (4.6%) were of American Society of Anesthesiologists Physical Status Classification System III or higher. The median duration of mechanical ventilation in the intensive care unit was 280 min (IQR, 526 min). Multivariable analysis revealed that premedication with benzodiazepines (odds ratio (OR) 2.60, 95% confidence interval (0.99; 6.81)), the male sex (OR 2.43, 95% confidence interval (1.10; 5.36)), and the duration of surgery (OR 1.54, 95% confidence interval (1.07; 2.23)) were associated with prolonged mechanical ventilation. By contrast, total intravenous anesthesia was associated with shorter ventilation time (OR 0.19, 95% confidence interval (0.09; 0.43)). Conclusion: premedication with benzodiazepines, the male sex, and the duration of surgery might be considered to be independent risk factors for delayed extubation in patients undergoing bimaxillary surgery. |
| first_indexed | 2024-03-09T10:27:37Z |
| format | Article |
| id | doaj.art-d6e79d655e904c06a10a33c88addc1ee |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-09T10:27:37Z |
| publishDate | 2022-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-d6e79d655e904c06a10a33c88addc1ee2023-12-01T21:33:01ZengMDPI AGJournal of Clinical Medicine2077-03832022-07-011113382910.3390/jcm11133829Risk Factors for Prolonged Mechanical Ventilation and Delayed Extubation Following Bimaxillary Orthognathic Surgery: A Single-Center Retrospective Cohort StudyChristian I. Schwer0Teresa Roth1Mathieu Gass2René Rothweiler3Torsten Loop4Marc C. Metzger5Johannes Kalbhenn6Department of Anesthesiology and Intensive Care Medicine, University Medical Center Freiburg, 79106 Freiburg, GermanyDepartment of Oral and Maxillofacial Surgery, University Medical Center Freiburg, 79106 Freiburg, GermanyDepartment of Oral and Maxillofacial Surgery, University Medical Center Freiburg, 79106 Freiburg, GermanyDepartment of Oral and Maxillofacial Surgery, University Medical Center Freiburg, 79106 Freiburg, GermanyDepartment of Anesthesiology and Intensive Care Medicine, University Medical Center Freiburg, 79106 Freiburg, GermanyDepartment of Oral and Maxillofacial Surgery, University Medical Center Freiburg, 79106 Freiburg, GermanyDepartment of Anesthesiology and Intensive Care Medicine, University Medical Center Freiburg, 79106 Freiburg, GermanyBackground: Bimaxillary orthognathic surgery bears the risk of severe postoperative airway complications. There are no clear recommendations for immediate postoperative follow-up and monitoring. Objective: to identify potential risk factors for prolonged mechanical ventilation and delayed extubation in patients undergoing bimaxillary orthognathic surgery. Methods: The data of all consecutive patients undergoing bimaxillary surgery between May 2012 and October 2019 were analyzed in a single-center retrospective cohort study. The clinical data were evaluated regarding baseline characteristics and potential factors linked with delayed extubation. Results: A total of 195 patients were included; 54.9% were female, and the median age was 23 years (IQR 5). The median body mass index was 23.1 (IQR 8). Nine patients (4.6%) were of American Society of Anesthesiologists Physical Status Classification System III or higher. The median duration of mechanical ventilation in the intensive care unit was 280 min (IQR, 526 min). Multivariable analysis revealed that premedication with benzodiazepines (odds ratio (OR) 2.60, 95% confidence interval (0.99; 6.81)), the male sex (OR 2.43, 95% confidence interval (1.10; 5.36)), and the duration of surgery (OR 1.54, 95% confidence interval (1.07; 2.23)) were associated with prolonged mechanical ventilation. By contrast, total intravenous anesthesia was associated with shorter ventilation time (OR 0.19, 95% confidence interval (0.09; 0.43)). Conclusion: premedication with benzodiazepines, the male sex, and the duration of surgery might be considered to be independent risk factors for delayed extubation in patients undergoing bimaxillary surgery.https://www.mdpi.com/2077-0383/11/13/3829bimaxillary surgeryairway complicationsrisk factorsextubation |
| spellingShingle | Christian I. Schwer Teresa Roth Mathieu Gass René Rothweiler Torsten Loop Marc C. Metzger Johannes Kalbhenn Risk Factors for Prolonged Mechanical Ventilation and Delayed Extubation Following Bimaxillary Orthognathic Surgery: A Single-Center Retrospective Cohort Study Journal of Clinical Medicine bimaxillary surgery airway complications risk factors extubation |
| title | Risk Factors for Prolonged Mechanical Ventilation and Delayed Extubation Following Bimaxillary Orthognathic Surgery: A Single-Center Retrospective Cohort Study |
| title_full | Risk Factors for Prolonged Mechanical Ventilation and Delayed Extubation Following Bimaxillary Orthognathic Surgery: A Single-Center Retrospective Cohort Study |
| title_fullStr | Risk Factors for Prolonged Mechanical Ventilation and Delayed Extubation Following Bimaxillary Orthognathic Surgery: A Single-Center Retrospective Cohort Study |
| title_full_unstemmed | Risk Factors for Prolonged Mechanical Ventilation and Delayed Extubation Following Bimaxillary Orthognathic Surgery: A Single-Center Retrospective Cohort Study |
| title_short | Risk Factors for Prolonged Mechanical Ventilation and Delayed Extubation Following Bimaxillary Orthognathic Surgery: A Single-Center Retrospective Cohort Study |
| title_sort | risk factors for prolonged mechanical ventilation and delayed extubation following bimaxillary orthognathic surgery a single center retrospective cohort study |
| topic | bimaxillary surgery airway complications risk factors extubation |
| url | https://www.mdpi.com/2077-0383/11/13/3829 |
| work_keys_str_mv | AT christianischwer riskfactorsforprolongedmechanicalventilationanddelayedextubationfollowingbimaxillaryorthognathicsurgeryasinglecenterretrospectivecohortstudy AT teresaroth riskfactorsforprolongedmechanicalventilationanddelayedextubationfollowingbimaxillaryorthognathicsurgeryasinglecenterretrospectivecohortstudy AT mathieugass riskfactorsforprolongedmechanicalventilationanddelayedextubationfollowingbimaxillaryorthognathicsurgeryasinglecenterretrospectivecohortstudy AT renerothweiler riskfactorsforprolongedmechanicalventilationanddelayedextubationfollowingbimaxillaryorthognathicsurgeryasinglecenterretrospectivecohortstudy AT torstenloop riskfactorsforprolongedmechanicalventilationanddelayedextubationfollowingbimaxillaryorthognathicsurgeryasinglecenterretrospectivecohortstudy AT marccmetzger riskfactorsforprolongedmechanicalventilationanddelayedextubationfollowingbimaxillaryorthognathicsurgeryasinglecenterretrospectivecohortstudy AT johanneskalbhenn riskfactorsforprolongedmechanicalventilationanddelayedextubationfollowingbimaxillaryorthognathicsurgeryasinglecenterretrospectivecohortstudy |