<b>Electrochemical oxidation of niclosamide at a glassy carbon electrode and its determination by voltammetry</b>
Cyclic voltammetry, square-wave voltammetry and controlled potential electrolysis have been used to study the electrochemical oxidation behaviour of niclosamide at a glassy carbon electrode. The number of electrons transferred, the wave characteristics, the diffusion coefficient and reversibility of...
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| Format: | Article |
| Language: | English |
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Chemical Society of Ethiopia
2003-06-01
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| Series: | Bulletin of the Chemical Society of Ethiopia |
| Subjects: | |
| Online Access: | http://ajol.info/index.php/bcse/article/view/61740 |
| _version_ | 1818474812139372544 |
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| author | Hailemichael Alemu Ntai M. Khoabane Potlaki F. Tseki |
| author_facet | Hailemichael Alemu Ntai M. Khoabane Potlaki F. Tseki |
| author_sort | Hailemichael Alemu |
| collection | DOAJ |
| description | Cyclic voltammetry, square-wave voltammetry and controlled potential electrolysis have been used to study the electrochemical oxidation behaviour of niclosamide at a glassy carbon electrode. The number of electrons transferred, the wave characteristics, the diffusion coefficient and reversibility of the reactions have been investigated. Following optimisation of voltammetric parameters, pH, and reproducibility, a linear calibration curve over the range 1 x 10<sup>-6</sup> – 1 x 10<sup>-4</sup> mol dm<sup>-3</sup> niclosamide was achieved. The detection limit was found to be 8 x 10<sup>-7</sup> mol dm<sup>-3</sup>. For eight successive determinations of 1 x 10<sup>-5</sup> mol dm<sup>-3</sup> niclosamide, a relative standard deviation of 3.6% was obtained. This voltammetric method was applied for the determination of niclosamide in tablets. |
| first_indexed | 2024-04-14T04:42:18Z |
| format | Article |
| id | doaj.art-d6ea88b0f5bd4b61acfb39f27f1ee25e |
| institution | Directory Open Access Journal |
| issn | 1011-3924 1726-801X |
| language | English |
| last_indexed | 2024-04-14T04:42:18Z |
| publishDate | 2003-06-01 |
| publisher | Chemical Society of Ethiopia |
| record_format | Article |
| series | Bulletin of the Chemical Society of Ethiopia |
| spelling | doaj.art-d6ea88b0f5bd4b61acfb39f27f1ee25e2022-12-22T02:11:38ZengChemical Society of EthiopiaBulletin of the Chemical Society of Ethiopia1011-39241726-801X2003-06-0117195106<b>Electrochemical oxidation of niclosamide at a glassy carbon electrode and its determination by voltammetry</b>Hailemichael AlemuNtai M. KhoabanePotlaki F. TsekiCyclic voltammetry, square-wave voltammetry and controlled potential electrolysis have been used to study the electrochemical oxidation behaviour of niclosamide at a glassy carbon electrode. The number of electrons transferred, the wave characteristics, the diffusion coefficient and reversibility of the reactions have been investigated. Following optimisation of voltammetric parameters, pH, and reproducibility, a linear calibration curve over the range 1 x 10<sup>-6</sup> – 1 x 10<sup>-4</sup> mol dm<sup>-3</sup> niclosamide was achieved. The detection limit was found to be 8 x 10<sup>-7</sup> mol dm<sup>-3</sup>. For eight successive determinations of 1 x 10<sup>-5</sup> mol dm<sup>-3</sup> niclosamide, a relative standard deviation of 3.6% was obtained. This voltammetric method was applied for the determination of niclosamide in tablets.http://ajol.info/index.php/bcse/article/view/61740NiclosamideElectrochemical oxidationCyclic voltammetrySquare wave VoltammetryGlassy carbon electrodeDetermination of niclosamide |
| spellingShingle | Hailemichael Alemu Ntai M. Khoabane Potlaki F. Tseki <b>Electrochemical oxidation of niclosamide at a glassy carbon electrode and its determination by voltammetry</b> Bulletin of the Chemical Society of Ethiopia Niclosamide Electrochemical oxidation Cyclic voltammetry Square wave Voltammetry Glassy carbon electrode Determination of niclosamide |
| title | <b>Electrochemical oxidation of niclosamide at a glassy carbon electrode and its determination by voltammetry</b> |
| title_full | <b>Electrochemical oxidation of niclosamide at a glassy carbon electrode and its determination by voltammetry</b> |
| title_fullStr | <b>Electrochemical oxidation of niclosamide at a glassy carbon electrode and its determination by voltammetry</b> |
| title_full_unstemmed | <b>Electrochemical oxidation of niclosamide at a glassy carbon electrode and its determination by voltammetry</b> |
| title_short | <b>Electrochemical oxidation of niclosamide at a glassy carbon electrode and its determination by voltammetry</b> |
| title_sort | b electrochemical oxidation of niclosamide at a glassy carbon electrode and its determination by voltammetry b |
| topic | Niclosamide Electrochemical oxidation Cyclic voltammetry Square wave Voltammetry Glassy carbon electrode Determination of niclosamide |
| url | http://ajol.info/index.php/bcse/article/view/61740 |
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