Familial mediterranean fever complicated by chronic kidney disease stage 5 description of the clinical case
this clinical case demonstrates renal amyloidosis – the most severe complication of familial Mediterranean fever (FMF). This clinical case gives an example of rapid evolution of renal failure in the lack of treatment. 62 years old man, Armenian, consults a physician with such complaints as evening...
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| Format: | Article |
| Language: | English |
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Bogomolets National Medical University
2021-12-01
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| Series: | Ukrainian Scientific Medical Youth Journal |
| Subjects: | |
| Online Access: | https://mmj.nmuofficial.com/index.php/journal/article/view/845 |
| _version_ | 1828184637851041792 |
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| author | Maria Palchukovska Lyudmila Liksunova |
| author_facet | Maria Palchukovska Lyudmila Liksunova |
| author_sort | Maria Palchukovska |
| collection | DOAJ |
| description | this clinical case demonstrates renal amyloidosis – the most severe complication of familial Mediterranean fever (FMF). This clinical case gives an example of rapid evolution of renal failure in the lack of treatment. 62 years old man, Armenian, consults a physician with such complaints as evening fever up to 38° for a month, frequent urination and dark urine. Biochemical blood test revealed an increase in the following indices: creatinine-489 μmol / l, urea 28.3 μmol / l, uric acid 619 μmol / l. GFR-6ml / min. No amyloid deposits were detected by biopsy of the buccal mucosa. The diagnosis of FMF, chronic kidney disease (CKD) stage 5. Initiation of treatment. Tenkhoff catheter installation. Treatment includes сontinuous ambulatory peritoneal dialysis (CAPD) in mode 4 exchanges with a glucose solution of 1.36% 2.0 liters. The dynamics of treatment is positive in presence of constant replacement therapy. A feature of this clinical case is the insidious development of secondary (AA) amyloidosis in uncontrolled patient, which leads to the development of end-stage chronic kidney disease (CKD). This case demonstrates the need of constant examination and treatment of the patients with end-stage CKD by renal replacement therapy, which significantly reduces the quality of patient`s life. |
| first_indexed | 2024-04-12T06:52:04Z |
| format | Article |
| id | doaj.art-d6ee9973ff4e41ac96352ce6e5287d2b |
| institution | Directory Open Access Journal |
| issn | 2786-6661 2786-667X |
| language | English |
| last_indexed | 2024-04-12T06:52:04Z |
| publishDate | 2021-12-01 |
| publisher | Bogomolets National Medical University |
| record_format | Article |
| series | Ukrainian Scientific Medical Youth Journal |
| spelling | doaj.art-d6ee9973ff4e41ac96352ce6e5287d2b2022-12-22T03:43:18ZengBogomolets National Medical UniversityUkrainian Scientific Medical Youth Journal2786-66612786-667X2021-12-011274444710.32345/USMYJ.4(127).2021.44-47845Familial mediterranean fever complicated by chronic kidney disease stage 5 description of the clinical caseMaria Palchukovska0Lyudmila Liksunova1Bogomolets National Medical University, Kyiv, UkraineCandidate of Medical Sciences, Chief Physician of the Institute of Nephrology of the National Academy of Medical Sciences of Ukrainethis clinical case demonstrates renal amyloidosis – the most severe complication of familial Mediterranean fever (FMF). This clinical case gives an example of rapid evolution of renal failure in the lack of treatment. 62 years old man, Armenian, consults a physician with such complaints as evening fever up to 38° for a month, frequent urination and dark urine. Biochemical blood test revealed an increase in the following indices: creatinine-489 μmol / l, urea 28.3 μmol / l, uric acid 619 μmol / l. GFR-6ml / min. No amyloid deposits were detected by biopsy of the buccal mucosa. The diagnosis of FMF, chronic kidney disease (CKD) stage 5. Initiation of treatment. Tenkhoff catheter installation. Treatment includes сontinuous ambulatory peritoneal dialysis (CAPD) in mode 4 exchanges with a glucose solution of 1.36% 2.0 liters. The dynamics of treatment is positive in presence of constant replacement therapy. A feature of this clinical case is the insidious development of secondary (AA) amyloidosis in uncontrolled patient, which leads to the development of end-stage chronic kidney disease (CKD). This case demonstrates the need of constant examination and treatment of the patients with end-stage CKD by renal replacement therapy, which significantly reduces the quality of patient`s life.https://mmj.nmuofficial.com/index.php/journal/article/view/845amyloidosis, familial mediterranean fever, nephrotic syndrome, renal insufficiency, peritoneal dialysis |
| spellingShingle | Maria Palchukovska Lyudmila Liksunova Familial mediterranean fever complicated by chronic kidney disease stage 5 description of the clinical case Ukrainian Scientific Medical Youth Journal amyloidosis, familial mediterranean fever, nephrotic syndrome, renal insufficiency, peritoneal dialysis |
| title | Familial mediterranean fever complicated by chronic kidney disease stage 5 description of the clinical case |
| title_full | Familial mediterranean fever complicated by chronic kidney disease stage 5 description of the clinical case |
| title_fullStr | Familial mediterranean fever complicated by chronic kidney disease stage 5 description of the clinical case |
| title_full_unstemmed | Familial mediterranean fever complicated by chronic kidney disease stage 5 description of the clinical case |
| title_short | Familial mediterranean fever complicated by chronic kidney disease stage 5 description of the clinical case |
| title_sort | familial mediterranean fever complicated by chronic kidney disease stage 5 description of the clinical case |
| topic | amyloidosis, familial mediterranean fever, nephrotic syndrome, renal insufficiency, peritoneal dialysis |
| url | https://mmj.nmuofficial.com/index.php/journal/article/view/845 |
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