Maternal B Cell-Intrinsic MyD88 Signaling Mediates LPS-Driven Intrauterine Fetal Death

Maternal B Cell-Intrinsic MyD88 Signaling Mediates LPS-Driven Intrauterine Fetal Death

Immunological networks balance tolerance towards paternal alloantigens during pregnancy with normal immune response to pathogens. Subclinical infections can impact this balance and lead to preterm birth or even intrauterine fetal death (IUFD). We recently showed that loss of maternal B cells renders...

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Bibliographic Details
Main Authors: Mandy Busse, Susanne Plenagl, Norina Kim Jutta Campe, Andreas J. Müller, Kerry Tedford, Anne Schumacher, Ana Claudia Zenclussen
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Cells
Subjects:
intrauterine fetal death
pregnancy
inflammation
B cells
Online Access:https://www.mdpi.com/2073-4409/10/10/2693

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