NOTCH3 promotes malignant progression of bladder cancer by directly regulating SPP1 and activating PI3K/AKT pathway
Abstract The biological role and precise molecular mechanisms of Notch receptor 3 (NOTCH3) in the malignant progression of bladder cancer (BLCA) remain unclear. In this study, we found that NOTCH3 was significantly upregulated and associated with poor prognosis in BLCA patients. Functional experimen...
Autors principals: | , , , , , , |
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Format: | Article |
Idioma: | English |
Publicat: |
Nature Publishing Group
2024-11-01
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Col·lecció: | Cell Death and Disease |
Accés en línia: | https://doi.org/10.1038/s41419-024-07241-0 |