Progress in the efficacy and mechanism of spinal cord stimulation in neuropathological pain

Abstract Neuropathic pain (NP) is a long‐term recurrent disease caused by somatosensory nervous system injury, with spontaneous pain, hyperalgesia, ectopic pain, and paresthesia as the main clinical manifestations. It adversely affects patients' quality of life. NP treatments often include medi...

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Main Authors: Shun‐Lian Li, Jing Li, Hui‐Chan Xu, Yu‐Cong Liu, Ting‐Ting Yang, Hao Yuan
Format: Article
Language:English
Published: Wiley-VCH 2022-03-01
Series:Ibrain
Subjects:
Online Access:https://doi.org/10.1002/ibra.12020
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author Shun‐Lian Li
Jing Li
Hui‐Chan Xu
Yu‐Cong Liu
Ting‐Ting Yang
Hao Yuan
author_facet Shun‐Lian Li
Jing Li
Hui‐Chan Xu
Yu‐Cong Liu
Ting‐Ting Yang
Hao Yuan
author_sort Shun‐Lian Li
collection DOAJ
description Abstract Neuropathic pain (NP) is a long‐term recurrent disease caused by somatosensory nervous system injury, with spontaneous pain, hyperalgesia, ectopic pain, and paresthesia as the main clinical manifestations. It adversely affects patients' quality of life. NP treatments often include medication, physical therapy, and invasive therapy; the first two therapies are generally ineffective for some NP patients. These patients sometimes rely on invasive therapy to alleviate pain. Spinal cord stimulation (SCS) is a very effective therapeutic method. SCS is a neuroregulatory method that involves placing the electrodes on the corresponding painful spinal cords. Pain is greatly alleviated after SCS. SCS has been proven to be an effective therapeutic method for the treatment of neurological pain. Furthermore, SCS provides a feasible approach for patients with unsuccessful drug treatment. This paper reviews the relevant literature of spinal cord electrical stimulation, focusing on the mechanism of action, clinical application, clinical efficacy and technical progress of spinal cord electrical stimulation. SCS is widely used in the treatment of NP diseases such as postherpetic neuralgia, back surgery failure syndrome, and phantom limb pain. With advancements in science and technology, tremendous progress has also been made in the spinal cord electrical stimulation method and good momentum has been maintained.
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spelling doaj.art-d6f7d9062e41462b884be42bf97d8e8c2022-12-22T00:37:57ZengWiley-VCHIbrain2769-27952022-03-0181233610.1002/ibra.12020Progress in the efficacy and mechanism of spinal cord stimulation in neuropathological painShun‐Lian Li0Jing Li1Hui‐Chan Xu2Yu‐Cong Liu3Ting‐Ting Yang4Hao Yuan5Department of Anesthesia Zunyi Medical University Zunyi Guizhou ChinaDepartment of Anesthesia Zunyi Medical University Zunyi Guizhou ChinaDepartment of Anesthesia Zunyi Medical University Zunyi Guizhou ChinaDepartment of Anesthesia Zunyi Medical University Zunyi Guizhou ChinaDepartment of Anesthesia Zunyi Medical University Zunyi Guizhou ChinaSchool of Basic Medicine Kunming Medical University Kunming Yunnan ChinaAbstract Neuropathic pain (NP) is a long‐term recurrent disease caused by somatosensory nervous system injury, with spontaneous pain, hyperalgesia, ectopic pain, and paresthesia as the main clinical manifestations. It adversely affects patients' quality of life. NP treatments often include medication, physical therapy, and invasive therapy; the first two therapies are generally ineffective for some NP patients. These patients sometimes rely on invasive therapy to alleviate pain. Spinal cord stimulation (SCS) is a very effective therapeutic method. SCS is a neuroregulatory method that involves placing the electrodes on the corresponding painful spinal cords. Pain is greatly alleviated after SCS. SCS has been proven to be an effective therapeutic method for the treatment of neurological pain. Furthermore, SCS provides a feasible approach for patients with unsuccessful drug treatment. This paper reviews the relevant literature of spinal cord electrical stimulation, focusing on the mechanism of action, clinical application, clinical efficacy and technical progress of spinal cord electrical stimulation. SCS is widely used in the treatment of NP diseases such as postherpetic neuralgia, back surgery failure syndrome, and phantom limb pain. With advancements in science and technology, tremendous progress has also been made in the spinal cord electrical stimulation method and good momentum has been maintained.https://doi.org/10.1002/ibra.12020efficacyneuropathological painprogress of mechanismspinal cord stimulation
spellingShingle Shun‐Lian Li
Jing Li
Hui‐Chan Xu
Yu‐Cong Liu
Ting‐Ting Yang
Hao Yuan
Progress in the efficacy and mechanism of spinal cord stimulation in neuropathological pain
Ibrain
efficacy
neuropathological pain
progress of mechanism
spinal cord stimulation
title Progress in the efficacy and mechanism of spinal cord stimulation in neuropathological pain
title_full Progress in the efficacy and mechanism of spinal cord stimulation in neuropathological pain
title_fullStr Progress in the efficacy and mechanism of spinal cord stimulation in neuropathological pain
title_full_unstemmed Progress in the efficacy and mechanism of spinal cord stimulation in neuropathological pain
title_short Progress in the efficacy and mechanism of spinal cord stimulation in neuropathological pain
title_sort progress in the efficacy and mechanism of spinal cord stimulation in neuropathological pain
topic efficacy
neuropathological pain
progress of mechanism
spinal cord stimulation
url https://doi.org/10.1002/ibra.12020
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