Evolutionary principles and synthetic biology: avoiding a molecular tragedy of the commons with an engineered phage
<p>Abstract</p> <p>Background</p> <p>In prior work, adding a gene to phage T7 that degraded the host K1 capsule facilitated growth when plated on capsulated hosts. However, the transgenic protein (an endosialidase) is expressed as an exoenzyme, released from the cell at...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2012-09-01
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| Series: | Journal of Biological Engineering |
| Online Access: | http://www.jbioleng.org/content/6/1/13 |