RIF1 promotes human epithelial ovarian cancer growth and progression via activating human telomerase reverse transcriptase expression

RIF1 promotes human epithelial ovarian cancer growth and progression via activating human telomerase reverse transcriptase expression

Abstract Background Human telomerase reverse transcriptase (hTERT) is highly expressed in over 80% of tumors, including human epithelial ovarian cancer (EOC). However, the mechanisms through which hTERT is up-regulated in EOC and promotes tumor progression remain unclear. The aim of this study is to...

Full description

Bibliographic Details
Main Authors: Yong-Bin Liu, Ying Mei, Jing Long, Yu Zhang, Dong-Li Hu, Hong-Hao Zhou
Format: Article
Language:English
Published: BMC 2018-08-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Ovarian cancer
RIF1
Telomerase reverse transcriptase
hTERT
Online Access:http://link.springer.com/article/10.1186/s13046-018-0854-8

Similar Items

Similar Items