Machine learning predicts translation initiation sites in neurologic diseases with nucleotide repeat expansions.
A number of neurologic diseases associated with expanded nucleotide repeats, including an inherited form of amyotrophic lateral sclerosis, have an unconventional form of translation called repeat-associated non-AUG (RAN) translation. It has been speculated that the repeat regions in the RNA fold int...
Main Authors: | Alec C Gleason, Ghanashyam Ghadge, Jin Chen, Yoshifumi Sonobe, Raymond P Roos |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2022-01-01
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Series: | PLoS ONE |
Online Access: | https://doi.org/10.1371/journal.pone.0256411 |
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