Associations of increased spatial QRS-T angle with cardiovascular risk factors: data from the regional sample of ESSE-RF study
Aim. To study the associations of increased spatial QRS-T angle (sQRS-Ta ≥90°) with cardiovascular risk factors (RFs).Material and methods. We analyzed 1411 electrocardiography (ECG) records of men and women aged 25-64 years from a random regional sample of the Epidemiology of Cardiovascular Disease...
| Main Authors: | , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
«SILICEA-POLIGRAF» LLC
2021-09-01
|
| Series: | Кардиоваскулярная терапия и профилактика |
| Subjects: | |
| Online Access: | https://cardiovascular.elpub.ru/jour/article/view/3000 |
| _version_ | 1827063730984189952 |
|---|---|
| author | G. A. Muromtseva E. A.-I. Aidu Yu. K. Makarova V. A. Kutsenko E. B. Yarovaya V. G. Trunov Yu. A. Balanova A. V. Kapustina S. E. Evstifeeva A. Yu. Efanov S. A. Shalnova O. M. Drapkina |
| author_facet | G. A. Muromtseva E. A.-I. Aidu Yu. K. Makarova V. A. Kutsenko E. B. Yarovaya V. G. Trunov Yu. A. Balanova A. V. Kapustina S. E. Evstifeeva A. Yu. Efanov S. A. Shalnova O. M. Drapkina |
| author_sort | G. A. Muromtseva |
| collection | DOAJ |
| description | Aim. To study the associations of increased spatial QRS-T angle (sQRS-Ta ≥90°) with cardiovascular risk factors (RFs).Material and methods. We analyzed 1411 electrocardiography (ECG) records of men and women aged 25-64 years from a random regional sample of the Epidemiology of Cardiovascular Diseases and their Risk Factors in Regions of Russian Federation (ESSE-RF) study. Relationships of sQRS-Ta with the following RFs were assessed: hypertension (HTN), systolic blood pressure (SBP) ≥140 mm Hg, diastolic BP (DBP) ≥90 mm Hg, pulse pressure (PP) ≥60 mm Hg; glucose ≥7,0 mmol/l, hypercholesterolemia; hypertriglyceridemia; high-density lipoprotein cholesterol (HDL-C) ≤1,0/1,2 mmol/l in men/women, low-density lipoprotein cholesterol (LDL-C) >3,0 mmol/l; C-reactive protein (CRP) >1 mg/L; overweight, obesity and abdominal obesity; heart rate (HR) >80 bpm; age >52 years.Results. Weak but significant correlations of sQRS-Ta with age (in women), SBP, DBP, PP, body mass index, waist circumference, lipids, glucose, CRP were revealed. Univariate logistic regression demonstrated significant associations of increased sQRS-Ta with HTN, elevated SBP and PP, overweight, obesity and abdominal obesity, hypercholesterolemia, elevated LDL-C and CRP, hyperglycemia, age >52 years and heart rate >80 bpm. There were no associations of increased sQRS-Ta with male sex, elevated DBP, smoking, hypertriglyceridemia, and low HDL-C levels. The sQRS-Ta associations characteristic of women was similar with associations found among the entire sample. Men with increased sQRS-Ta had no associations with any of analyzed RFs. In multivariate models, increased sQRS-Ta was associated with the following combination of RFs: age >52 years, heart rate >80 bpm, HTN, increased PP, overwaight, and male sex. According to direct stepwise selection among all subjects and in women, the main contribution to sQRS-Ta was made by SBP, age, HDL-C and heart rate.Conclusion. Despite the significance of stepwise regression model (p=0,0001), the low coefficient of determination R2 may indicate other not yet identified determinants with relevant associations with sQRS-Ta. |
| first_indexed | 2024-04-10T03:34:31Z |
| format | Article |
| id | doaj.art-d6fca4d74d4141c48e132af9bb9c8d30 |
| institution | Directory Open Access Journal |
| issn | 1728-8800 2619-0125 |
| language | Russian |
| last_indexed | 2025-03-19T22:35:54Z |
| publishDate | 2021-09-01 |
| publisher | «SILICEA-POLIGRAF» LLC |
| record_format | Article |
| series | Кардиоваскулярная терапия и профилактика |
| spelling | doaj.art-d6fca4d74d4141c48e132af9bb9c8d302024-10-17T12:21:41Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252021-09-0120510.15829/1728-8800-2021-30002309Associations of increased spatial QRS-T angle with cardiovascular risk factors: data from the regional sample of ESSE-RF studyG. A. Muromtseva0E. A.-I. Aidu1Yu. K. Makarova2V. A. Kutsenko3E. B. Yarovaya4V. G. Trunov5Yu. A. Balanova6A. V. Kapustina7S. E. Evstifeeva8A. Yu. Efanov9S. A. Shalnova10O. M. Drapkina11National Medical Research Center of Therapy and Preventive MedicineNational Medical Research Center of Therapy and Preventive MedicineNational Medical Research Center of Therapy and Preventive Medicine; Lomonosov Moscow State UniversityNational Medical Research Center of Therapy and Preventive Medicine; Lomonosov Moscow State UniversityNational Medical Research Center of Therapy and Preventive Medicine; Lomonosov Moscow State UniversityA.A. Kharkevich Institute for Information Transmission ProblemsNational Medical Research Center of Therapy and Preventive MedicineNational Medical Research Center of Therapy and Preventive MedicineNational Medical Research Center of Therapy and Preventive MedicineTyumen State Medical University; Scientific and Practical Medical CenterNational Medical Research Center of Therapy and Preventive MedicineNational Medical Research Center of Therapy and Preventive MedicineAim. To study the associations of increased spatial QRS-T angle (sQRS-Ta ≥90°) with cardiovascular risk factors (RFs).Material and methods. We analyzed 1411 electrocardiography (ECG) records of men and women aged 25-64 years from a random regional sample of the Epidemiology of Cardiovascular Diseases and their Risk Factors in Regions of Russian Federation (ESSE-RF) study. Relationships of sQRS-Ta with the following RFs were assessed: hypertension (HTN), systolic blood pressure (SBP) ≥140 mm Hg, diastolic BP (DBP) ≥90 mm Hg, pulse pressure (PP) ≥60 mm Hg; glucose ≥7,0 mmol/l, hypercholesterolemia; hypertriglyceridemia; high-density lipoprotein cholesterol (HDL-C) ≤1,0/1,2 mmol/l in men/women, low-density lipoprotein cholesterol (LDL-C) >3,0 mmol/l; C-reactive protein (CRP) >1 mg/L; overweight, obesity and abdominal obesity; heart rate (HR) >80 bpm; age >52 years.Results. Weak but significant correlations of sQRS-Ta with age (in women), SBP, DBP, PP, body mass index, waist circumference, lipids, glucose, CRP were revealed. Univariate logistic regression demonstrated significant associations of increased sQRS-Ta with HTN, elevated SBP and PP, overweight, obesity and abdominal obesity, hypercholesterolemia, elevated LDL-C and CRP, hyperglycemia, age >52 years and heart rate >80 bpm. There were no associations of increased sQRS-Ta with male sex, elevated DBP, smoking, hypertriglyceridemia, and low HDL-C levels. The sQRS-Ta associations characteristic of women was similar with associations found among the entire sample. Men with increased sQRS-Ta had no associations with any of analyzed RFs. In multivariate models, increased sQRS-Ta was associated with the following combination of RFs: age >52 years, heart rate >80 bpm, HTN, increased PP, overwaight, and male sex. According to direct stepwise selection among all subjects and in women, the main contribution to sQRS-Ta was made by SBP, age, HDL-C and heart rate.Conclusion. Despite the significance of stepwise regression model (p=0,0001), the low coefficient of determination R2 may indicate other not yet identified determinants with relevant associations with sQRS-Ta.https://cardiovascular.elpub.ru/jour/article/view/3000spatial qrs-t anglecardiovascular risk factorspopulation studyesse-rf |
| spellingShingle | G. A. Muromtseva E. A.-I. Aidu Yu. K. Makarova V. A. Kutsenko E. B. Yarovaya V. G. Trunov Yu. A. Balanova A. V. Kapustina S. E. Evstifeeva A. Yu. Efanov S. A. Shalnova O. M. Drapkina Associations of increased spatial QRS-T angle with cardiovascular risk factors: data from the regional sample of ESSE-RF study Кардиоваскулярная терапия и профилактика spatial qrs-t angle cardiovascular risk factors population study esse-rf |
| title | Associations of increased spatial QRS-T angle with cardiovascular risk factors: data from the regional sample of ESSE-RF study |
| title_full | Associations of increased spatial QRS-T angle with cardiovascular risk factors: data from the regional sample of ESSE-RF study |
| title_fullStr | Associations of increased spatial QRS-T angle with cardiovascular risk factors: data from the regional sample of ESSE-RF study |
| title_full_unstemmed | Associations of increased spatial QRS-T angle with cardiovascular risk factors: data from the regional sample of ESSE-RF study |
| title_short | Associations of increased spatial QRS-T angle with cardiovascular risk factors: data from the regional sample of ESSE-RF study |
| title_sort | associations of increased spatial qrs t angle with cardiovascular risk factors data from the regional sample of esse rf study |
| topic | spatial qrs-t angle cardiovascular risk factors population study esse-rf |
| url | https://cardiovascular.elpub.ru/jour/article/view/3000 |
| work_keys_str_mv | AT gamuromtseva associationsofincreasedspatialqrstanglewithcardiovascularriskfactorsdatafromtheregionalsampleofesserfstudy AT eaiaidu associationsofincreasedspatialqrstanglewithcardiovascularriskfactorsdatafromtheregionalsampleofesserfstudy AT yukmakarova associationsofincreasedspatialqrstanglewithcardiovascularriskfactorsdatafromtheregionalsampleofesserfstudy AT vakutsenko associationsofincreasedspatialqrstanglewithcardiovascularriskfactorsdatafromtheregionalsampleofesserfstudy AT ebyarovaya associationsofincreasedspatialqrstanglewithcardiovascularriskfactorsdatafromtheregionalsampleofesserfstudy AT vgtrunov associationsofincreasedspatialqrstanglewithcardiovascularriskfactorsdatafromtheregionalsampleofesserfstudy AT yuabalanova associationsofincreasedspatialqrstanglewithcardiovascularriskfactorsdatafromtheregionalsampleofesserfstudy AT avkapustina associationsofincreasedspatialqrstanglewithcardiovascularriskfactorsdatafromtheregionalsampleofesserfstudy AT seevstifeeva associationsofincreasedspatialqrstanglewithcardiovascularriskfactorsdatafromtheregionalsampleofesserfstudy AT ayuefanov associationsofincreasedspatialqrstanglewithcardiovascularriskfactorsdatafromtheregionalsampleofesserfstudy AT sashalnova associationsofincreasedspatialqrstanglewithcardiovascularriskfactorsdatafromtheregionalsampleofesserfstudy AT omdrapkina associationsofincreasedspatialqrstanglewithcardiovascularriskfactorsdatafromtheregionalsampleofesserfstudy |