The model of electrified cell clusters in biological tissues basing on the resting potential difference
The resting potential is the potential difference that exists between the inner and outer sides of the cell membrane when the cell is not stimulated. The resting membrane potential is a key regulator of phenomena such as cell proliferation, morphogenesis, migration and differentiation. In this paper...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-06-01
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| Series: | Medicine in Novel Technology and Devices |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2590093523000139 |
| _version_ | 1827912041025765376 |
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| author | Yufang He Peiguo Xu Huijie Wu Yong Chu Guanglei Zhang |
| author_facet | Yufang He Peiguo Xu Huijie Wu Yong Chu Guanglei Zhang |
| author_sort | Yufang He |
| collection | DOAJ |
| description | The resting potential is the potential difference that exists between the inner and outer sides of the cell membrane when the cell is not stimulated. The resting membrane potential is a key regulator of phenomena such as cell proliferation, morphogenesis, migration and differentiation. In this paper, we proposed a model of electrified cell clusters that considers the resting potential of cell clusters in the resting state. By measuring the potential difference between the inner and outer sides of biological tissues, it is verified that the cell cluster has a negative potential difference when taking the outer potential as the reference. In the absence of external conductors, the tissue is electrically neutral; while in the presence of external conductors, the positive net charges escape freely under repulsive forces and the biological tissues form a negative electrical equilibrium system. The model proposed in this study explored the potential situation above the cellular level in the resting state, providing a new perspective for the research on resting potential. |
| first_indexed | 2024-03-13T02:10:31Z |
| format | Article |
| id | doaj.art-d6fd7bf7f372409fbb220e1b85070f47 |
| institution | Directory Open Access Journal |
| issn | 2590-0935 |
| language | English |
| last_indexed | 2024-03-13T02:10:31Z |
| publishDate | 2023-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Medicine in Novel Technology and Devices |
| spelling | doaj.art-d6fd7bf7f372409fbb220e1b85070f472023-07-01T04:35:33ZengElsevierMedicine in Novel Technology and Devices2590-09352023-06-0118100218The model of electrified cell clusters in biological tissues basing on the resting potential differenceYufang He0Peiguo Xu1Huijie Wu2Yong Chu3Guanglei Zhang4Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, Beihang University, Beijing, 100191, ChinaYantai Yuhuangding Hospital, Yantai, Shandong Province, 264000, ChinaBeijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, Beihang University, Beijing, 100191, ChinaInstitute of Animal Husbandry and Veterinary Medicine, Beijing Academy of Agriculture and Forestry Sciences, Beijing, 100097, China; Corresponding author.Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, Beihang University, Beijing, 100191, China; Corresponding author.The resting potential is the potential difference that exists between the inner and outer sides of the cell membrane when the cell is not stimulated. The resting membrane potential is a key regulator of phenomena such as cell proliferation, morphogenesis, migration and differentiation. In this paper, we proposed a model of electrified cell clusters that considers the resting potential of cell clusters in the resting state. By measuring the potential difference between the inner and outer sides of biological tissues, it is verified that the cell cluster has a negative potential difference when taking the outer potential as the reference. In the absence of external conductors, the tissue is electrically neutral; while in the presence of external conductors, the positive net charges escape freely under repulsive forces and the biological tissues form a negative electrical equilibrium system. The model proposed in this study explored the potential situation above the cellular level in the resting state, providing a new perspective for the research on resting potential.http://www.sciencedirect.com/science/article/pii/S2590093523000139Electrified cell clustersNegative electrical equilibrium systemResting potentialBiological tissues |
| spellingShingle | Yufang He Peiguo Xu Huijie Wu Yong Chu Guanglei Zhang The model of electrified cell clusters in biological tissues basing on the resting potential difference Medicine in Novel Technology and Devices Electrified cell clusters Negative electrical equilibrium system Resting potential Biological tissues |
| title | The model of electrified cell clusters in biological tissues basing on the resting potential difference |
| title_full | The model of electrified cell clusters in biological tissues basing on the resting potential difference |
| title_fullStr | The model of electrified cell clusters in biological tissues basing on the resting potential difference |
| title_full_unstemmed | The model of electrified cell clusters in biological tissues basing on the resting potential difference |
| title_short | The model of electrified cell clusters in biological tissues basing on the resting potential difference |
| title_sort | model of electrified cell clusters in biological tissues basing on the resting potential difference |
| topic | Electrified cell clusters Negative electrical equilibrium system Resting potential Biological tissues |
| url | http://www.sciencedirect.com/science/article/pii/S2590093523000139 |
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