Impaired intratumoral natural killer cell function in head and neck carcinoma

Impaired intratumoral natural killer cell function in head and neck carcinoma

Natural killer (NK) cells are emerging as unique players in the immune response against cancer; however, only limited data are available on tumor infiltrating NK cells in head and neck squamous cell carcinoma (HNSCC), one of the most common cancer. Occurrence of HNSCC is closely related to the immun...

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Bibliographic Details
Main Authors: Dalila Mele, Greta Pessino, Giuseppe Trisolini, Alberto Luchena, Marco Benazzo, Patrizia Morbini, Stefania Mantovani, Barbara Oliviero, Mario U. Mondelli, Stefania Varchetta
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Immunology
Subjects:
tumor microenvironment
HNSCC
natural killer cells
GITR
PD-1
NKG2C
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.997806/full

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