Trio-based GWAS identifies novel associations and subtype-specific risk factors for cleft palate

Trio-based GWAS identifies novel associations and subtype-specific risk factors for cleft palate

Summary: Cleft palate (CP) is one of the most common craniofacial birth defects; however, there are relatively few established genetic risk factors associated with its occurrence despite high heritability. Historically, CP has been studied as a single phenotype, although it manifests across a spectr...

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Bibliographic Details
Main Authors: Kelsey Robinson, Trenell J. Mosley, Kenneth S. Rivera-González, Christopher R. Jabbarpour, Sarah W. Curtis, Wasiu Lanre Adeyemo, Terri H. Beaty, Azeez Butali, Carmen J. Buxó, David J. Cutler, Michael P. Epstein, Lord J.J. Gowans, Jacqueline T. Hecht, Jeffrey C. Murray, Gary M. Shaw, Lina Moreno Uribe, Seth M. Weinberg, Harrison Brand, Mary L. Marazita, Robert J. Lipinski, Elizabeth J. Leslie
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:HGG Advances
Subjects:
palate
palatogenesis
osteogenesis
genome sequencing
GWAS
subtype
Online Access:http://www.sciencedirect.com/science/article/pii/S2666247723000660

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