Preliminary study on early diagnosis of Alzheimer’s disease in APP/PS1 transgenic mice using multimodal magnetic resonance imaging

Preliminary study on early diagnosis of Alzheimer’s disease in APP/PS1 transgenic mice using multimodal magnetic resonance imaging

Alzheimer’s disease (AD) has an insidious onset and lacks clear early diagnostic markers, and by the time overt dementia symptoms appear, the disease is already in the mid-to-late stages. The search for early diagnostic markers of AD may open a critical window for Alzheimer’s treatment and facilitat...

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Bibliographic Details
Main Authors: Meng Xu, Jipeng Liu, Qingguo Liu, Yu Gong, Yinyin Li, Jing Zhang, Shufeng Shi, Yuanyuan Shi
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Aging Neuroscience
Subjects:
Alzheimer’s disease
APP/PS1 transgenic mice
early diagnosis
sMRI
rs-fMRI
1H-MRS
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2024.1326394/full

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