Intracellular Exposure Dose-Associated Susceptibility of Steatotic Hepatocytes to Metallic Nanoparticles

Intracellular Exposure Dose-Associated Susceptibility of Steatotic Hepatocytes to Metallic Nanoparticles

Non-alcoholic fatty liver disease (NAFLD), mainly characterized by the accumulation of excess fat in hepatocytes, is the most prevalent liver disorder afflicting ~25% of adults worldwide. In vivo studies have shown that adult rodents with NAFLD were more sensitive to metallic nanoparticles (MNPs) th...

Full description

Bibliographic Details
Main Authors: Xiaoli Zhang, Yongyi Wei, Chengjun Li, Weiyu Wang, Rui Zhang, Jianbo Jia, Bing Yan
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:International Journal of Molecular Sciences
Subjects:
susceptible population
nanotoxicity
steatotic hepatocytes
lipid metabolism
intracellular exposure dose
Online Access:https://www.mdpi.com/1422-0067/22/23/12643

Similar Items

Similar Items