ALS-Linked SOD1 Mutants Enhance Neurite Outgrowth and Branching in Adult Motor Neurons

ALS-Linked SOD1 Mutants Enhance Neurite Outgrowth and Branching in Adult Motor Neurons

Summary: Amyotrophic lateral sclerosis (ALS) is a progressive, fatal neurodegenerative disease characterized by motor neuron cell death. However, not all motor neurons are equally susceptible. Most of what we know about the surviving motor neurons comes from gene expression profiling; less is known...

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Main Authors: Zachary Osking, Jacob I. Ayers, Ryan Hildebrandt, Kristen Skruber, Hilda Brown, Daniel Ryu, Amanda R. Eukovich, Todd E. Golde, David R. Borchelt, Tracy-Ann Read, Eric A. Vitriol
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:iScience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004218302566

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