Anthropometric parameters as a tool for the prediction of metabolic and cardiovascular risk in childhood brain tumor survivors
Abstract Purpose To assess the prevalence of alterations in anthropometric parameters predictive of metabolic syndrome and cardiovascular risk among childhood brain tumor survivors. Methods Anthropometric parameters predictive of metabolic syndrome and cardiovascular risk were analyzed [height, weig...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2024-01-01
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| Series: | Diabetology & Metabolic Syndrome |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13098-024-01262-7 |
| _version_ | 1797349812415234048 |
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| author | Alberto Romano Mariapia Masino Serena Rivetti Stefano Mastrangelo Giorgio Attinà Palma Maurizi Antonio Ruggiero |
| author_facet | Alberto Romano Mariapia Masino Serena Rivetti Stefano Mastrangelo Giorgio Attinà Palma Maurizi Antonio Ruggiero |
| author_sort | Alberto Romano |
| collection | DOAJ |
| description | Abstract Purpose To assess the prevalence of alterations in anthropometric parameters predictive of metabolic syndrome and cardiovascular risk among childhood brain tumor survivors. Methods Anthropometric parameters predictive of metabolic syndrome and cardiovascular risk were analyzed [height, weight, BMI, waist circumference, hip circumference, waist-height ratio (WHtR), waist-hip ratio (WHR, blood pressure] of 25 patients who survived childhood brain tumors. Results 21 patients (84%) showed alteration of at least one predictive anthropometric parameter. 11 patients (44%) showed a BMI > 75th percentile and 19 patients (76%) showed a pathological WHR value. A pathological WHtR (> 0.5), was identified in 17 patients (68%); the average WHtR observed was 0.53. 9 patients (36%) showed an alteration of all three anthropometric parameters considered. Comparing this subpopulation with the subpopulation with less than three altered parameters, a greater prevalence of the combined alteration was observed in the female sex compared to the male sex (67% vs. 26%). No significant differences were observed regarding the age of diagnosis and end of treatment nor the treatments carried out (chemotherapy, radiotherapy, steroid therapy) between the two groups. Conclusion These results suggest that this population is at high risk of presenting pathological values of BMI, WHR and WHtR with consequent high risk of developing metabolic syndrome and cardiovascular diseases. |
| first_indexed | 2024-03-08T12:35:52Z |
| format | Article |
| id | doaj.art-d70727ae02a54180b7b2fd2c6e6b88ff |
| institution | Directory Open Access Journal |
| issn | 1758-5996 |
| language | English |
| last_indexed | 2024-03-08T12:35:52Z |
| publishDate | 2024-01-01 |
| publisher | BMC |
| record_format | Article |
| series | Diabetology & Metabolic Syndrome |
| spelling | doaj.art-d70727ae02a54180b7b2fd2c6e6b88ff2024-01-21T12:28:54ZengBMCDiabetology & Metabolic Syndrome1758-59962024-01-011611810.1186/s13098-024-01262-7Anthropometric parameters as a tool for the prediction of metabolic and cardiovascular risk in childhood brain tumor survivorsAlberto Romano0Mariapia Masino1Serena Rivetti2Stefano Mastrangelo3Giorgio Attinà4Palma Maurizi5Antonio Ruggiero6Pediatric Oncology Unit, Fondazione Policlinico Universitario Agostino Gemelli IRCCSPediatric Oncology Unit, Fondazione Policlinico Universitario Agostino Gemelli IRCCSPediatric Oncology Unit, Fondazione Policlinico Universitario Agostino Gemelli IRCCSPediatric Oncology Unit, Fondazione Policlinico Universitario Agostino Gemelli IRCCSPediatric Oncology Unit, Fondazione Policlinico Universitario Agostino Gemelli IRCCSPediatric Oncology Unit, Fondazione Policlinico Universitario Agostino Gemelli IRCCSPediatric Oncology Unit, Fondazione Policlinico Universitario Agostino Gemelli IRCCSAbstract Purpose To assess the prevalence of alterations in anthropometric parameters predictive of metabolic syndrome and cardiovascular risk among childhood brain tumor survivors. Methods Anthropometric parameters predictive of metabolic syndrome and cardiovascular risk were analyzed [height, weight, BMI, waist circumference, hip circumference, waist-height ratio (WHtR), waist-hip ratio (WHR, blood pressure] of 25 patients who survived childhood brain tumors. Results 21 patients (84%) showed alteration of at least one predictive anthropometric parameter. 11 patients (44%) showed a BMI > 75th percentile and 19 patients (76%) showed a pathological WHR value. A pathological WHtR (> 0.5), was identified in 17 patients (68%); the average WHtR observed was 0.53. 9 patients (36%) showed an alteration of all three anthropometric parameters considered. Comparing this subpopulation with the subpopulation with less than three altered parameters, a greater prevalence of the combined alteration was observed in the female sex compared to the male sex (67% vs. 26%). No significant differences were observed regarding the age of diagnosis and end of treatment nor the treatments carried out (chemotherapy, radiotherapy, steroid therapy) between the two groups. Conclusion These results suggest that this population is at high risk of presenting pathological values of BMI, WHR and WHtR with consequent high risk of developing metabolic syndrome and cardiovascular diseases.https://doi.org/10.1186/s13098-024-01262-7Brain tumorMetabolic syndromeCardiovascular riskChildhood cancer survivor |
| spellingShingle | Alberto Romano Mariapia Masino Serena Rivetti Stefano Mastrangelo Giorgio Attinà Palma Maurizi Antonio Ruggiero Anthropometric parameters as a tool for the prediction of metabolic and cardiovascular risk in childhood brain tumor survivors Diabetology & Metabolic Syndrome Brain tumor Metabolic syndrome Cardiovascular risk Childhood cancer survivor |
| title | Anthropometric parameters as a tool for the prediction of metabolic and cardiovascular risk in childhood brain tumor survivors |
| title_full | Anthropometric parameters as a tool for the prediction of metabolic and cardiovascular risk in childhood brain tumor survivors |
| title_fullStr | Anthropometric parameters as a tool for the prediction of metabolic and cardiovascular risk in childhood brain tumor survivors |
| title_full_unstemmed | Anthropometric parameters as a tool for the prediction of metabolic and cardiovascular risk in childhood brain tumor survivors |
| title_short | Anthropometric parameters as a tool for the prediction of metabolic and cardiovascular risk in childhood brain tumor survivors |
| title_sort | anthropometric parameters as a tool for the prediction of metabolic and cardiovascular risk in childhood brain tumor survivors |
| topic | Brain tumor Metabolic syndrome Cardiovascular risk Childhood cancer survivor |
| url | https://doi.org/10.1186/s13098-024-01262-7 |
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