Osteosarcoma of the larynx: treatment outcomes and patterns of failure analysis
The incidence of laryngeal sarcoma is exceedingly low with osteosarcomas of the larynx being rarer still, comprising less than 1% of all associated malignancies. To date, only 32 cases have been reported since this pathologic entity was first described in 1942. In this article, we discuss the most r...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2017-03-01
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| Series: | Rare Tumors |
| Subjects: | |
| Online Access: | http://www.pagepress.org/journals/index.php/rt/article/view/6955 |
| _version_ | 1818693320412495872 |
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| author | Nathan R. Bennion Michael J. Baine Timothy Malouff Weining Zhen |
| author_facet | Nathan R. Bennion Michael J. Baine Timothy Malouff Weining Zhen |
| author_sort | Nathan R. Bennion |
| collection | DOAJ |
| description | The incidence of laryngeal sarcoma is exceedingly low with osteosarcomas of the larynx being rarer still, comprising less than 1% of all associated malignancies. To date, only 32 cases have been reported since this pathologic entity was first described in 1942. In this article, we discuss the most recent case of laryngeal osteosarcoma in a patient presenting with respiratory distress found to be due to a tumor mass arising from her cricoid cartilage. We further summarize current knowledge regarding the epidemiology, presentation, and diagnosis of this uncommon disease. Lastly, we synthesize all available information regarding treatment and outcomes of the 32 previously described cases of osteosarcoma of the larynx as well as the presently described case in an attempt to offer some insight regarding optimal treatment in future cases. |
| first_indexed | 2024-12-17T13:11:49Z |
| format | Article |
| id | doaj.art-d707e88fa89a45c19742b436a8320baa |
| institution | Directory Open Access Journal |
| issn | 2036-3605 2036-3613 |
| language | English |
| last_indexed | 2024-12-17T13:11:49Z |
| publishDate | 2017-03-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Rare Tumors |
| spelling | doaj.art-d707e88fa89a45c19742b436a8320baa2022-12-21T21:47:06ZengSAGE PublishingRare Tumors2036-36052036-36132017-03-019110.4081/rt.2017.69553666Osteosarcoma of the larynx: treatment outcomes and patterns of failure analysisNathan R. Bennion0Michael J. Baine1Timothy Malouff2Weining Zhen3Department of Radiation Oncology, University of Nebraska Medical Center, Omaha, NEDepartment of Radiation Oncology, University of Nebraska Medical Center, Omaha, NECreighton University Medical Center, Omaha, NEDepartment of Radiation Oncology, University of Nebraska Medical Center, Omaha, NEThe incidence of laryngeal sarcoma is exceedingly low with osteosarcomas of the larynx being rarer still, comprising less than 1% of all associated malignancies. To date, only 32 cases have been reported since this pathologic entity was first described in 1942. In this article, we discuss the most recent case of laryngeal osteosarcoma in a patient presenting with respiratory distress found to be due to a tumor mass arising from her cricoid cartilage. We further summarize current knowledge regarding the epidemiology, presentation, and diagnosis of this uncommon disease. Lastly, we synthesize all available information regarding treatment and outcomes of the 32 previously described cases of osteosarcoma of the larynx as well as the presently described case in an attempt to offer some insight regarding optimal treatment in future cases.http://www.pagepress.org/journals/index.php/rt/article/view/6955Larynx, Osteosarcoma, Chemoradiation, Surgery |
| spellingShingle | Nathan R. Bennion Michael J. Baine Timothy Malouff Weining Zhen Osteosarcoma of the larynx: treatment outcomes and patterns of failure analysis Rare Tumors Larynx, Osteosarcoma, Chemoradiation, Surgery |
| title | Osteosarcoma of the larynx: treatment outcomes and patterns of failure analysis |
| title_full | Osteosarcoma of the larynx: treatment outcomes and patterns of failure analysis |
| title_fullStr | Osteosarcoma of the larynx: treatment outcomes and patterns of failure analysis |
| title_full_unstemmed | Osteosarcoma of the larynx: treatment outcomes and patterns of failure analysis |
| title_short | Osteosarcoma of the larynx: treatment outcomes and patterns of failure analysis |
| title_sort | osteosarcoma of the larynx treatment outcomes and patterns of failure analysis |
| topic | Larynx, Osteosarcoma, Chemoradiation, Surgery |
| url | http://www.pagepress.org/journals/index.php/rt/article/view/6955 |
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