Towards personalised anti-microbial and immune approaches to infections in acute care. Can real-time genomic-informed diagnosis of pathogens, and immune-focused therapies improve outcomes for patients? An observational, experimental study protocol.

Towards personalised anti-microbial and immune approaches to infections in acute care. Can real-time genomic-informed diagnosis of pathogens, and immune-focused therapies improve outcomes for patients? An observational, experimental study protocol.

<h4>Introduction</h4>Infection causes a vast burden of disease, with significant mortality, morbidity and costs to health-care systems. However, identifying the pathogen causative infection can be challenging, resulting in high use of broad-spectrum antibiotics, much of which may be inap...

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Bibliographic Details
Main Authors: Samuel Quarton, Kirsty McGee, Nicola Cumley, Mahboobeh Behruznia, Charlotte Jeff, Kylie Belchamber, Michael Cox, David Thickett, Aaron Scott, Dhruv Parekh, Alan McNally, Elizabeth Sapey
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0298425&type=printable

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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0298425&type=printable

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