Infectious hematopoietic necrosis virus: advances in diagnosis and vaccine development
The aquaculture of salmonid fishes is a multi-billion dollar industry with production over 3 million tons annually. However, infectious hematopoietic necrosis virus (IHNV), which infects and kills salmon and trout, significantly reduces the revenue of the salmon farming industry. Currently, there is...
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| Format: | Article |
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PeerJ Inc.
2019-07-01
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| Series: | PeerJ |
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| Online Access: | https://peerj.com/articles/7151.pdf |
| _version_ | 1797425709297172480 |
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| author | Chean Yeah Yong Hui Kian Ong Hooi Chia Tang Swee Keong Yeap Abdul Rahman Omar Kok Lian Ho Wen Siang Tan |
| author_facet | Chean Yeah Yong Hui Kian Ong Hooi Chia Tang Swee Keong Yeap Abdul Rahman Omar Kok Lian Ho Wen Siang Tan |
| author_sort | Chean Yeah Yong |
| collection | DOAJ |
| description | The aquaculture of salmonid fishes is a multi-billion dollar industry with production over 3 million tons annually. However, infectious hematopoietic necrosis virus (IHNV), which infects and kills salmon and trout, significantly reduces the revenue of the salmon farming industry. Currently, there is no effective treatment for IHNV infected fishes; therefore, early detection and depopulation of the infected fishes remain the most common practices to contain the spread of IHNV. Apart from hygiene practices in aquaculture and isolation of infected fishes, loss of fishes due to IHNV infection can also be significantly reduced through vaccination programs. In the current review, some of the diagnostic methods for IHNV, spanning from clinical diagnosis to cell culture, serological and molecular methods are discussed in detail. In addition, some of the most significant candidate vaccines for IHNV are also extensively discussed, particularly the DNA vaccines. |
| first_indexed | 2024-03-09T08:20:04Z |
| format | Article |
| id | doaj.art-d70de6ac74974cfa8fab423a825cdc40 |
| institution | Directory Open Access Journal |
| issn | 2167-8359 |
| language | English |
| last_indexed | 2024-03-09T08:20:04Z |
| publishDate | 2019-07-01 |
| publisher | PeerJ Inc. |
| record_format | Article |
| series | PeerJ |
| spelling | doaj.art-d70de6ac74974cfa8fab423a825cdc402023-12-02T21:53:51ZengPeerJ Inc.PeerJ2167-83592019-07-017e715110.7717/peerj.7151Infectious hematopoietic necrosis virus: advances in diagnosis and vaccine developmentChean Yeah Yong0Hui Kian Ong1Hooi Chia Tang2Swee Keong Yeap3Abdul Rahman Omar4Kok Lian Ho5Wen Siang Tan6Department of Microbiology, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, Serdang, Selangor, MalaysiaDepartment of Pathology, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Selangor, MalaysiaLaboratory of Vaccines and Immunotherapeutics, Institute of Bioscience, Universiti Putra Malaysia, Serdang, Selangor, MalaysiaChina ASEAN College of Marine Sciences, Xiamen University Malaysia, Sepang, Selangor, MalaysiaLaboratory of Vaccines and Immunotherapeutics, Institute of Bioscience, Universiti Putra Malaysia, Serdang, Selangor, MalaysiaDepartment of Pathology, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Selangor, MalaysiaDepartment of Microbiology, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, Serdang, Selangor, MalaysiaThe aquaculture of salmonid fishes is a multi-billion dollar industry with production over 3 million tons annually. However, infectious hematopoietic necrosis virus (IHNV), which infects and kills salmon and trout, significantly reduces the revenue of the salmon farming industry. Currently, there is no effective treatment for IHNV infected fishes; therefore, early detection and depopulation of the infected fishes remain the most common practices to contain the spread of IHNV. Apart from hygiene practices in aquaculture and isolation of infected fishes, loss of fishes due to IHNV infection can also be significantly reduced through vaccination programs. In the current review, some of the diagnostic methods for IHNV, spanning from clinical diagnosis to cell culture, serological and molecular methods are discussed in detail. In addition, some of the most significant candidate vaccines for IHNV are also extensively discussed, particularly the DNA vaccines.https://peerj.com/articles/7151.pdfRhabdovirusInfectious hematopoietic necrosis virusDNA vaccineDiagnosisVaccine |
| spellingShingle | Chean Yeah Yong Hui Kian Ong Hooi Chia Tang Swee Keong Yeap Abdul Rahman Omar Kok Lian Ho Wen Siang Tan Infectious hematopoietic necrosis virus: advances in diagnosis and vaccine development PeerJ Rhabdovirus Infectious hematopoietic necrosis virus DNA vaccine Diagnosis Vaccine |
| title | Infectious hematopoietic necrosis virus: advances in diagnosis and vaccine development |
| title_full | Infectious hematopoietic necrosis virus: advances in diagnosis and vaccine development |
| title_fullStr | Infectious hematopoietic necrosis virus: advances in diagnosis and vaccine development |
| title_full_unstemmed | Infectious hematopoietic necrosis virus: advances in diagnosis and vaccine development |
| title_short | Infectious hematopoietic necrosis virus: advances in diagnosis and vaccine development |
| title_sort | infectious hematopoietic necrosis virus advances in diagnosis and vaccine development |
| topic | Rhabdovirus Infectious hematopoietic necrosis virus DNA vaccine Diagnosis Vaccine |
| url | https://peerj.com/articles/7151.pdf |
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