The Clinical Guiding Role of the Distribution of Corneal Nerves in the Selection of Incision for Penetrating Corneal Surgery in Canines
The cornea is one of the regions with the highest density of nerve terminals in the animal body and it bears such functions as nourishing the cornea and maintaining corneal sensation. In veterinary clinical practice, the corneoscleral limbus incision is frequently applied in cataract surgery, periph...
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MDPI AG
2021-12-01
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| Series: | Veterinary Sciences |
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| Online Access: | https://www.mdpi.com/2306-7381/8/12/313 |
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| author | Zichen Liu Chang Yu Yiwen Song Mo Pang Yipeng Jin |
| author_facet | Zichen Liu Chang Yu Yiwen Song Mo Pang Yipeng Jin |
| author_sort | Zichen Liu |
| collection | DOAJ |
| description | The cornea is one of the regions with the highest density of nerve terminals in the animal body and it bears such functions as nourishing the cornea and maintaining corneal sensation. In veterinary clinical practice, the corneoscleral limbus incision is frequently applied in cataract surgery, peripheral iridectomy, and other procedures for glaucoma. Inevitably, it would cause damage to the nerve roots that enter the cornea from the corneal limbus, thus inducing a series of complications. In this paper, the in vitro cornea (39 corneas from 23 canines, with ages ranging from 8 months old to 3 years old, including 12 male canines and 11 female canines) was divided into 6 zones, and the whole cornea was stained with gold chloride. After staining, corneal nerves formed neural networks at different levels of cornea. There was no significant difference in the number of nerve roots at the corneoscleral limbus between different zones (F = 1.983, <i>p</i> = 0.082), and the nerve roots at the corneoscleral limbus (mean value, 24.43; 95% CI, 23.43–25.42) were evenly distributed. Additionally, there was no significant difference in the number of corneal nerve roots between male and female canines (<i>p</i> = 0.143). There was also no significant difference in the number of corneal nerve roots between adult canines and puppies (<i>p</i> = 0.324). The results of the above analysis will provide a reasonable anatomical basis for selecting the incision location and orientation of penetrating surgery for the canine cornea in veterinary practice. |
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| issn | 2306-7381 |
| language | English |
| last_indexed | 2024-03-10T03:56:32Z |
| publishDate | 2021-12-01 |
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| series | Veterinary Sciences |
| spelling | doaj.art-d70eb694ca7046c2b8a00c02929fbc882023-11-23T10:55:56ZengMDPI AGVeterinary Sciences2306-73812021-12-0181231310.3390/vetsci8120313The Clinical Guiding Role of the Distribution of Corneal Nerves in the Selection of Incision for Penetrating Corneal Surgery in CaninesZichen Liu0Chang Yu1Yiwen Song2Mo Pang3Yipeng Jin4College of Veterinary Medicine, People’s Republic of China Agricultural University, No. 2 Yuanmingyuan West Rd, Haidian District, Beijing 100193, ChinaCollege of Veterinary Medicine, People’s Republic of China Agricultural University, No. 2 Yuanmingyuan West Rd, Haidian District, Beijing 100193, ChinaCollege of Veterinary Medicine, People’s Republic of China Agricultural University, No. 2 Yuanmingyuan West Rd, Haidian District, Beijing 100193, ChinaCollege of Veterinary Medicine, People’s Republic of China Agricultural University, No. 2 Yuanmingyuan West Rd, Haidian District, Beijing 100193, ChinaCollege of Veterinary Medicine, People’s Republic of China Agricultural University, No. 2 Yuanmingyuan West Rd, Haidian District, Beijing 100193, ChinaThe cornea is one of the regions with the highest density of nerve terminals in the animal body and it bears such functions as nourishing the cornea and maintaining corneal sensation. In veterinary clinical practice, the corneoscleral limbus incision is frequently applied in cataract surgery, peripheral iridectomy, and other procedures for glaucoma. Inevitably, it would cause damage to the nerve roots that enter the cornea from the corneal limbus, thus inducing a series of complications. In this paper, the in vitro cornea (39 corneas from 23 canines, with ages ranging from 8 months old to 3 years old, including 12 male canines and 11 female canines) was divided into 6 zones, and the whole cornea was stained with gold chloride. After staining, corneal nerves formed neural networks at different levels of cornea. There was no significant difference in the number of nerve roots at the corneoscleral limbus between different zones (F = 1.983, <i>p</i> = 0.082), and the nerve roots at the corneoscleral limbus (mean value, 24.43; 95% CI, 23.43–25.42) were evenly distributed. Additionally, there was no significant difference in the number of corneal nerve roots between male and female canines (<i>p</i> = 0.143). There was also no significant difference in the number of corneal nerve roots between adult canines and puppies (<i>p</i> = 0.324). The results of the above analysis will provide a reasonable anatomical basis for selecting the incision location and orientation of penetrating surgery for the canine cornea in veterinary practice.https://www.mdpi.com/2306-7381/8/12/313caninecorneal nerve staininggold chloridecorneal incision |
| spellingShingle | Zichen Liu Chang Yu Yiwen Song Mo Pang Yipeng Jin The Clinical Guiding Role of the Distribution of Corneal Nerves in the Selection of Incision for Penetrating Corneal Surgery in Canines Veterinary Sciences canine corneal nerve staining gold chloride corneal incision |
| title | The Clinical Guiding Role of the Distribution of Corneal Nerves in the Selection of Incision for Penetrating Corneal Surgery in Canines |
| title_full | The Clinical Guiding Role of the Distribution of Corneal Nerves in the Selection of Incision for Penetrating Corneal Surgery in Canines |
| title_fullStr | The Clinical Guiding Role of the Distribution of Corneal Nerves in the Selection of Incision for Penetrating Corneal Surgery in Canines |
| title_full_unstemmed | The Clinical Guiding Role of the Distribution of Corneal Nerves in the Selection of Incision for Penetrating Corneal Surgery in Canines |
| title_short | The Clinical Guiding Role of the Distribution of Corneal Nerves in the Selection of Incision for Penetrating Corneal Surgery in Canines |
| title_sort | clinical guiding role of the distribution of corneal nerves in the selection of incision for penetrating corneal surgery in canines |
| topic | canine corneal nerve staining gold chloride corneal incision |
| url | https://www.mdpi.com/2306-7381/8/12/313 |
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