Golgi Fragmentation in Alzheimer’s Disease

Golgi Fragmentation in Alzheimer’s Disease

The Golgi apparatus is an essential cellular organelle for post-translational modifications, sorting, and trafficking of membrane and secretory proteins. Proper functionality of the Golgi requires the formation of its unique cisternal-stacking morphology. The Golgi structure is disrupted in a variet...

Full description

Bibliographic Details
Main Authors:	Gunjan eJoshi, Michael eBekier, Yanzhuang eWang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2015-09-01
Series:	Frontiers in Neuroscience
Subjects:	Phosphorylation Golgi Alzheimer’s disease Amyloid beta amyloid precursor protein GRASP65
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fnins.2015.00340/full

Similar Items

GRASPs in Golgi Structure and Function
by: Xiaoyan eZhang, et al.
Published: (2016-01-01)

Sequential phosphorylation of GRASP65 during mitotic Golgi disassembly
by: Danming Tang, et al.
Published: (2012-09-01)

New Insights Into the Golgi Stacking Proteins
by: Erpan Ahat, et al.
Published: (2019-07-01)

Amyloidosis in Alzheimer’s Disease: Pathogeny, Etiology, and Related Therapeutic Directions
by: Chen Ma, et al.
Published: (2022-02-01)

Alzheimer’s disease: pathogenesis, diagnostics, and therapeutics
by: Tiwari S, et al.
Published: (2019-07-01)

The Golgi apparatus: Site for convergence of COVID-19 brain fog and Alzheimer’s disease?
by: Yanzhuang Wang, et al.
Published: (2022-10-01)

The Role of MicroRNAs in Aβ Deposition and Tau Phosphorylation in Alzheimer’s Disease
by: Juanjuan Zhao, et al.
Published: (2017-07-01)

Dreaming of a New World Where Alzheimer’s Is a Treatable Disorder
by: Marcella Catania, et al.
Published: (2019-11-01)

Current advances in the treatment of Alzheimer's disease: focused on considerations targeting Aβ and tau
by: Hong-Qi Yang, et al.
Published: (2012-10-01)

Exercise for the prevention of Alzheimer's disease: Multiple pathways to promote non-amyloidogenic AβPP processing
by: Richard J. Elsworthy, et al.
Published: (2022-09-01)

Potential Implications of miRNAs in the Pathogenesis, Diagnosis, and Therapeutics of Alzheimer’s Disease
by: Long Wang, et al.
Published: (2023-11-01)

Amyloid Beta in Aging and Alzheimer’s Disease
by: Ujala Sehar, et al.
Published: (2022-10-01)

Commentary: APP as a Mediator of the Synapse Pathology in Alzheimer's Disease
by: An Schreurs, et al.
Published: (2018-05-01)

In Vitro Studies of Flemish, Dutch, and Wild-Type β-Amyloid Provide Evidence for Two-Staged Neurotoxicity
by: Samir Kumar-Singh, et al.
Published: (2002-11-01)

Structural analysis and modeling comparison of primates' amyloid BA4 protein /
by: Fahimeh Jalali, 1987-, et al.
Published: (2013)

Structural analysis and modeling comparison of primates' amyloid BA4 protein [electronic resource] /
by: Fahimeh Jalali, 1987-
Published: (2013)

Excessive/Aberrant and Maladaptive Synaptic Plasticity: A Hypothesis for the Pathogenesis of Alzheimer’s Disease
by: Shigeki Kawabata
Published: (2022-07-01)

Sunday Driver Mediates Multi-Compartment Golgi Outposts Defects Induced by Amyloid Precursor Protein
by: Qianqian Du, et al.
Published: (2021-06-01)

Differential effects of familial Alzheimer’s disease-causing mutations on amyloid precursor protein (APP) trafficking, proteolytic conversion, and synaptogenic activity
by: Sandra Schilling, et al.
Published: (2023-06-01)

Prominent amyloid plaque pathology and cerebral amyloid angiopathy in APP V717I (London) carrier – phenotypic variability in autosomal dominant Alzheimer’s disease
by: Grace M. Lloyd, et al.
Published: (2020-03-01)

Peptidyl-Prolyl Cis/Trans Isomerase Pin1 and Alzheimer’s Disease
by: Long Wang, et al.
Published: (2020-05-01)

Review Paper: Tau Pathology of Alzheimer Disease: Possible Role of Sleep Deprivation
by: Nahid Ahmadian, et al.
Published: (2018-09-01)

Contribution of the Endosomal-Lysosomal and Proteasomal Systems in Amyloid-β Precursor Protein Derived Fragments Processing
by: Caroline Evrard, et al.
Published: (2018-11-01)

Editorial: Golgi Dynamics in Physiological and Pathological Conditions
by: Kristian Prydz, et al.
Published: (2020-01-01)

Amyloid Precursor Protein and Alzheimer’s Disease
by: Kseniia S. Orobets, et al.
Published: (2023-09-01)

Upregulation of endocytic protein expression in the Alzheimer’s disease male human brain
by: Mouhamed Alsaqati, et al.
Published: (2023-01-01)

Shifting the balance: soluble ADAM10 as a potential treatment for Alzheimer's disease
by: Ayelet Sarah Hershkovits, et al.
Published: (2023-05-01)

Wading pools and fading memories – place navigation in transgenic mouse models of Alzheimer’s disease
by: Heikki eTanila
Published: (2012-06-01)

Amyloid precursor protein : a practical approach /
by: Xia, Weiming, et al.
Published: (2005)

Alpha- and Gamma-Tocopherol Modulates the Amyloidogenic Pathway of Amyloid Precursor Protein in an in vitro Model of Alzheimer’s Disease: A Transcriptional Study
by: Aslina Pahrudin Arrozi, et al.
Published: (2022-05-01)

Abeta(1–40)-induced secretion of matrix metalloproteinase-9 results in sAPPα release by association with cell surface APP
by: Argiris A. Talamagas, et al.
Published: (2007-12-01)

Alzheimer disease and platelets: how’s that relevant
by: Catricala Silvia, et al.
Published: (2012-09-01)

Amyloid precursor protein in peripheral granulocytes as a potential biomarker for Alzheimer’s disease
by: Xiaonan Wang, et al.
Published: (2016-04-01)

Amyloid precursor protein in peripheral granulocytes as a potential biomarker for Alzheimers disease
by: Xiaonan Wang, et al.
Published: (2016-03-01)

SYSTEMIC AMYLOIDOSIS: FINDING ON AUTOPSY. REPORT OF TWO CASES (IN SPANISH)
by: Martínez-Muñoz Elsa, et al.
Published: (2014-01-01)

Involvement of 5-lipoxygenase activating protein in the amyloidotic phenotype of an Alzheimer’s disease mouse model
by: Chu Jin, et al.
Published: (2012-06-01)

Re-Arranging the Puzzle between the Amyloid-Beta and Tau Pathology: An APP-Centric Approach
by: Florence Haut, et al.
Published: (2023-12-01)

The Pursuit of the “Inside” of the Amyloid Hypothesis—Is C99 a Promising Therapeutic Target for Alzheimer’s Disease?
by: Nobumasa Takasugi, et al.
Published: (2023-01-01)

Sensory gamma entrainment: Impact on amyloid protein and therapeutic mechanism
by: Jiaying Hu, et al.
Published: (2023-10-01)

Knockdown of Amyloid Precursor Protein: Biological Consequences and Clinical Opportunities
by: Rebecca M. C. Gabriele, et al.
Published: (2022-03-01)