CXCL16 promotes tumor metastasis by regulating angiogenesis in the tumor micro-environment of BRAF V600E mutant colorectal cancer

CXCL16 promotes tumor metastasis by regulating angiogenesis in the tumor micro-environment of BRAF V600E mutant colorectal cancer

Patients of colorectal cancer (CRC) with BRAF V600E mutation obtain poor prognosis. This study aimed to explore the role and mechanism of BRAF V600E mutation in angiogenesis of tumor micro-environment (TME). It has been reported that CXCL16 expression in TME is closely related to BRAF mutation. Clin...

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Bibliographic Details
Main Authors: Weihao Deng, Xiaoxia Liu, Shuhui Huang, Zhijie Wu, Fichera Alessandro, Qingfeng Lin, Zonglu Cai, Zitong Zhang, Yan Huang, Hui Wang, Zixu Yuan
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Translational Oncology
Subjects:
CXCL16
BRAF V600E mutant
Colorectal cancer
Tumor micro-environment
Angiogenesis
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523323002401

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