Matairesinol Induces Mitochondrial Dysfunction and Exerts Synergistic Anticancer Effects with 5-Fluorouracil in Pancreatic Cancer Cells

Matairesinol Induces Mitochondrial Dysfunction and Exerts Synergistic Anticancer Effects with 5-Fluorouracil in Pancreatic Cancer Cells

Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive types of cancer and exhibits a devastating 5-year survival rate. The most recent procedure for the treatment of PDAC is a combination of several conventional chemotherapeutic agents, termed FOLFIRINOX, that includes irinotecan, le...

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Bibliographic Details
Main Authors: Woonghee Lee, Gwonhwa Song, Hyocheol Bae
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Marine Drugs
Subjects:
matairesinol
pancreatic cancer
mitochondria dysfunction
5-fluorouracil
anticancer drugs
Online Access:https://www.mdpi.com/1660-3397/20/8/473

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