Notch-1 Signaling Modulates Macrophage Polarization and Immune Defense against <i>Mycobacterium avium paratuberculosis</i> Infection in Inflammatory Diseases

Notch-1 Signaling Modulates Macrophage Polarization and Immune Defense against <i>Mycobacterium avium paratuberculosis</i> Infection in Inflammatory Diseases

Despite the extensive research on Notch signaling involvement in inflammation, its specific role in macrophage response in autoimmune disease and defense mechanisms against bacterial infection, such as <i>Mycobacterium avium paratuberculosis</i> (MAP), remains unknown. In this study, we...

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Bibliographic Details
Main Authors: Esra’a Keewan, Saleh A. Naser
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Microorganisms
Subjects:
notch
macrophages
paratuberculosis
IL-6
mcl-1
apoptosis
Online Access:https://www.mdpi.com/2076-2607/8/7/1006

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