Questions and Answers Related to the Prebiotic Production of Oligonucleotide Sequences from 3′,5′ Cyclic Nucleotide Precursors
Template-free nonenzymatic polymerization of 3′,5′ cyclic nucleotides is an emerging topic of the origin of life research. In the last ten years, a number of papers have been published addressing various aspects of this process. These works evoked a vivid discussion among scientists working in the f...
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MDPI AG
2021-08-01
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| Online Access: | https://www.mdpi.com/2075-1729/11/8/800 |
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| author | Judit E. Šponer Jiří Šponer Aleš Kovařík Ondrej Šedo Zbyněk Zdráhal Giovanna Costanzo Ernesto Di Mauro |
| author_facet | Judit E. Šponer Jiří Šponer Aleš Kovařík Ondrej Šedo Zbyněk Zdráhal Giovanna Costanzo Ernesto Di Mauro |
| author_sort | Judit E. Šponer |
| collection | DOAJ |
| description | Template-free nonenzymatic polymerization of 3′,5′ cyclic nucleotides is an emerging topic of the origin of life research. In the last ten years, a number of papers have been published addressing various aspects of this process. These works evoked a vivid discussion among scientists working in the field of prebiotic chemistry. The aim of the current review is to answer the most frequently raised questions related to the detection and characterization of oligomeric products as well as to the geological context of this chemistry. |
| first_indexed | 2024-03-10T08:40:25Z |
| format | Article |
| id | doaj.art-d71cf64c755540249b8b051dd51fd646 |
| institution | Directory Open Access Journal |
| issn | 2075-1729 |
| language | English |
| last_indexed | 2024-03-10T08:40:25Z |
| publishDate | 2021-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Life |
| spelling | doaj.art-d71cf64c755540249b8b051dd51fd6462023-11-22T08:23:05ZengMDPI AGLife2075-17292021-08-0111880010.3390/life11080800Questions and Answers Related to the Prebiotic Production of Oligonucleotide Sequences from 3′,5′ Cyclic Nucleotide PrecursorsJudit E. Šponer0Jiří Šponer1Aleš Kovařík2Ondrej Šedo3Zbyněk Zdráhal4Giovanna Costanzo5Ernesto Di Mauro6Institute of Biophysics of the Czech Academy of Sciences, Královopolská 135, 61265 Brno, Czech RepublicInstitute of Biophysics of the Czech Academy of Sciences, Královopolská 135, 61265 Brno, Czech RepublicInstitute of Biophysics of the Czech Academy of Sciences, Královopolská 135, 61265 Brno, Czech RepublicCentral European Institute of Technology, Masaryk University, Kamenice 5, 62500 Brno, Czech RepublicCentral European Institute of Technology, Masaryk University, Kamenice 5, 62500 Brno, Czech RepublicInstitute of Molecular Biology and Pathology, CNR, Piazzale A. Moro 5, 00185 Rome, ItalyInstitute of Molecular Biology and Pathology, CNR, Piazzale A. Moro 5, 00185 Rome, ItalyTemplate-free nonenzymatic polymerization of 3′,5′ cyclic nucleotides is an emerging topic of the origin of life research. In the last ten years, a number of papers have been published addressing various aspects of this process. These works evoked a vivid discussion among scientists working in the field of prebiotic chemistry. The aim of the current review is to answer the most frequently raised questions related to the detection and characterization of oligomeric products as well as to the geological context of this chemistry.https://www.mdpi.com/2075-1729/11/8/800polymerizationcyclic nucleotidesprebiotic chemistry |
| spellingShingle | Judit E. Šponer Jiří Šponer Aleš Kovařík Ondrej Šedo Zbyněk Zdráhal Giovanna Costanzo Ernesto Di Mauro Questions and Answers Related to the Prebiotic Production of Oligonucleotide Sequences from 3′,5′ Cyclic Nucleotide Precursors Life polymerization cyclic nucleotides prebiotic chemistry |
| title | Questions and Answers Related to the Prebiotic Production of Oligonucleotide Sequences from 3′,5′ Cyclic Nucleotide Precursors |
| title_full | Questions and Answers Related to the Prebiotic Production of Oligonucleotide Sequences from 3′,5′ Cyclic Nucleotide Precursors |
| title_fullStr | Questions and Answers Related to the Prebiotic Production of Oligonucleotide Sequences from 3′,5′ Cyclic Nucleotide Precursors |
| title_full_unstemmed | Questions and Answers Related to the Prebiotic Production of Oligonucleotide Sequences from 3′,5′ Cyclic Nucleotide Precursors |
| title_short | Questions and Answers Related to the Prebiotic Production of Oligonucleotide Sequences from 3′,5′ Cyclic Nucleotide Precursors |
| title_sort | questions and answers related to the prebiotic production of oligonucleotide sequences from 3 5 cyclic nucleotide precursors |
| topic | polymerization cyclic nucleotides prebiotic chemistry |
| url | https://www.mdpi.com/2075-1729/11/8/800 |
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