Test Characteristics of Urine Dipstick for Identifying Renal Insufficiency in Patients with Diabetes

Objective: To evaluate the test characteristics of the urine dipstick as a screening tool for elevated serum creatinine in patients with uncontrolled diabetes mellitus in the emergency department (ED).Methods: Patients with diabetes over the age of 18 who presented to the ED for any complaint over a...

Full description

Bibliographic Details
Main Authors: Arora, Sanjay, Long, Theodore, Menchine, Michael
Format: Article
Language:English
Published: eScholarship Publishing, University of California 2011-05-01
Series:Western Journal of Emergency Medicine
Subjects:
Online Access:http://escholarship.org/uc/item/50j700d1
_version_ 1818450053411373056
author Arora, Sanjay
Long, Theodore
Menchine, Michael
author_facet Arora, Sanjay
Long, Theodore
Menchine, Michael
author_sort Arora, Sanjay
collection DOAJ
description Objective: To evaluate the test characteristics of the urine dipstick as a screening tool for elevated serum creatinine in patients with uncontrolled diabetes mellitus in the emergency department (ED).Methods: Patients with diabetes over the age of 18 who presented to the ED for any complaint over a three-month study period were considered eligible for participation in this study. A finger-stick blood glucose of ≥250 mg/dL at triage was used to confirm the diagnosis of uncontrolled diabetes. After obtaining written consent, each patient had a urine dip performed and a chemistry panel drawn. Any level of proteinuria on the urine dip was considered to be a positive test. Based on the laboratory and clinical guidelines at our institution, renal insufficiency was defined as creatinine concentration of greater than 1.3 mg/dL.Results: Three Hundred ninety-three confirmed patients with uncontrolled diabetes were enrolled in this study, and 49 of these (12.5%) were found to have renal insufficiency. The sensitivity and specificity of the urine dip for predicting renal insufficiency were 69.4% (95% confidence interval [CI] 54.6-81.7%) and 57.8% (95%CI 52.4-63.1%) respectively. The positive predictive value was 19% (95%CI 13.5-25.5%), and the negative predictive value was 93% (95%CI 88.7-96%). The positive likelihood ratio was 1.65 (95%CI 1.32-2.06) and the negative likelihood ratio was 0.53 (95%CI 0.34-0.81).Conclusion: In this cohort of patients with uncontrolled diabetes, the test characteristics of the urine dipstick make it a poor screening tool for renal insufficiency in the ED. [West J Emerg Med. 2011;12(2):250-253.]
first_indexed 2024-12-14T20:45:11Z
format Article
id doaj.art-d725314e105f4646b6d05b48e1907a21
institution Directory Open Access Journal
issn 1936-900X
1936-9018
language English
last_indexed 2024-12-14T20:45:11Z
publishDate 2011-05-01
publisher eScholarship Publishing, University of California
record_format Article
series Western Journal of Emergency Medicine
spelling doaj.art-d725314e105f4646b6d05b48e1907a212022-12-21T22:48:05ZengeScholarship Publishing, University of CaliforniaWestern Journal of Emergency Medicine1936-900X1936-90182011-05-01122250253Test Characteristics of Urine Dipstick for Identifying Renal Insufficiency in Patients with DiabetesArora, SanjayLong, TheodoreMenchine, MichaelObjective: To evaluate the test characteristics of the urine dipstick as a screening tool for elevated serum creatinine in patients with uncontrolled diabetes mellitus in the emergency department (ED).Methods: Patients with diabetes over the age of 18 who presented to the ED for any complaint over a three-month study period were considered eligible for participation in this study. A finger-stick blood glucose of ≥250 mg/dL at triage was used to confirm the diagnosis of uncontrolled diabetes. After obtaining written consent, each patient had a urine dip performed and a chemistry panel drawn. Any level of proteinuria on the urine dip was considered to be a positive test. Based on the laboratory and clinical guidelines at our institution, renal insufficiency was defined as creatinine concentration of greater than 1.3 mg/dL.Results: Three Hundred ninety-three confirmed patients with uncontrolled diabetes were enrolled in this study, and 49 of these (12.5%) were found to have renal insufficiency. The sensitivity and specificity of the urine dip for predicting renal insufficiency were 69.4% (95% confidence interval [CI] 54.6-81.7%) and 57.8% (95%CI 52.4-63.1%) respectively. The positive predictive value was 19% (95%CI 13.5-25.5%), and the negative predictive value was 93% (95%CI 88.7-96%). The positive likelihood ratio was 1.65 (95%CI 1.32-2.06) and the negative likelihood ratio was 0.53 (95%CI 0.34-0.81).Conclusion: In this cohort of patients with uncontrolled diabetes, the test characteristics of the urine dipstick make it a poor screening tool for renal insufficiency in the ED. [West J Emerg Med. 2011;12(2):250-253.]http://escholarship.org/uc/item/50j700d1Urine DipstickScreeningRenal Insufficiency
spellingShingle Arora, Sanjay
Long, Theodore
Menchine, Michael
Test Characteristics of Urine Dipstick for Identifying Renal Insufficiency in Patients with Diabetes
Western Journal of Emergency Medicine
Urine Dipstick
Screening
Renal Insufficiency
title Test Characteristics of Urine Dipstick for Identifying Renal Insufficiency in Patients with Diabetes
title_full Test Characteristics of Urine Dipstick for Identifying Renal Insufficiency in Patients with Diabetes
title_fullStr Test Characteristics of Urine Dipstick for Identifying Renal Insufficiency in Patients with Diabetes
title_full_unstemmed Test Characteristics of Urine Dipstick for Identifying Renal Insufficiency in Patients with Diabetes
title_short Test Characteristics of Urine Dipstick for Identifying Renal Insufficiency in Patients with Diabetes
title_sort test characteristics of urine dipstick for identifying renal insufficiency in patients with diabetes
topic Urine Dipstick
Screening
Renal Insufficiency
url http://escholarship.org/uc/item/50j700d1
work_keys_str_mv AT arorasanjay testcharacteristicsofurinedipstickforidentifyingrenalinsufficiencyinpatientswithdiabetes
AT longtheodore testcharacteristicsofurinedipstickforidentifyingrenalinsufficiencyinpatientswithdiabetes
AT menchinemichael testcharacteristicsofurinedipstickforidentifyingrenalinsufficiencyinpatientswithdiabetes