A rare congenital malformation: caudal regression syndrome
Caudal regression is a rare syndrome which has a spectrum of congenital malformations ranging from simple anal atresia to absence of sacral, lumbar and possibly lower thoracic vertebrae. It results from a disturbance in the fetal mesoderm in early pregnancy (less than 4 greater than sup than less th...
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| Format: | Article |
| Language: | English |
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The Pan African Medical Journal
2013-01-01
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| Series: | The Pan African Medical Journal |
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| Online Access: |
https://www.panafrican-med-journal.com/content/article/14/30/pdf/30.pdf
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| _version_ | 1819001194020864000 |
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| author | Cherkaoui Mandour Brahim El Mostarchid |
| author_facet | Cherkaoui Mandour Brahim El Mostarchid |
| author_sort | Cherkaoui Mandour |
| collection | DOAJ |
| description | Caudal regression is a rare syndrome which has a spectrum of congenital malformations ranging from simple anal atresia to absence of sacral, lumbar and possibly lower thoracic vertebrae. It results from a disturbance in the fetal mesoderm in early pregnancy (less than 4 greater than sup than less than/sup greater than week of gestation). Maternal diabetes, genetic predisposition and vascular hypoperfusion have been suggested as possible causative factors but no true causative factor has been determined. Associated organ system dysfunction depends on the severity of the disease. Prenatal ultrasonographic diagnosis of this syndrome is possible at 22 weeks of gestation. We report a case of a four months old male newborn to a known diabetic mother. We present a bone reconstruction in 3D that shows a syringomyelia from D4 to D7; terminal myélocystocele (D10); agenesis of D11, D12, lumbar vertebrae, sacrum and coccyx; contiguous appearance of kidneys without prevertebral parenchymal bridge. |
| first_indexed | 2024-12-20T22:45:20Z |
| format | Article |
| id | doaj.art-d72b9d7666f6443b99eb161d02aed750 |
| institution | Directory Open Access Journal |
| issn | 1937-8688 1937-8688 |
| language | English |
| last_indexed | 2024-12-20T22:45:20Z |
| publishDate | 2013-01-01 |
| publisher | The Pan African Medical Journal |
| record_format | Article |
| series | The Pan African Medical Journal |
| spelling | doaj.art-d72b9d7666f6443b99eb161d02aed7502022-12-21T19:24:24ZengThe Pan African Medical JournalThe Pan African Medical Journal1937-86881937-86882013-01-01143010.11604/pamj.2013.14.30.23642364A rare congenital malformation: caudal regression syndromeCherkaoui Mandour0Brahim El Mostarchid1 Departement Of Neurosurgery, Military Hospital Mohammed V, Rabat, Morocco Departement Of Neurosurgery, Military Hospital Mohammed V, Rabat, Morocco Caudal regression is a rare syndrome which has a spectrum of congenital malformations ranging from simple anal atresia to absence of sacral, lumbar and possibly lower thoracic vertebrae. It results from a disturbance in the fetal mesoderm in early pregnancy (less than 4 greater than sup than less than/sup greater than week of gestation). Maternal diabetes, genetic predisposition and vascular hypoperfusion have been suggested as possible causative factors but no true causative factor has been determined. Associated organ system dysfunction depends on the severity of the disease. Prenatal ultrasonographic diagnosis of this syndrome is possible at 22 weeks of gestation. We report a case of a four months old male newborn to a known diabetic mother. We present a bone reconstruction in 3D that shows a syringomyelia from D4 to D7; terminal myélocystocele (D10); agenesis of D11, D12, lumbar vertebrae, sacrum and coccyx; contiguous appearance of kidneys without prevertebral parenchymal bridge. https://www.panafrican-med-journal.com/content/article/14/30/pdf/30.pdf caudal regression syndromecongenital malformationsyringomyeliavertebral agenesis |
| spellingShingle | Cherkaoui Mandour Brahim El Mostarchid A rare congenital malformation: caudal regression syndrome The Pan African Medical Journal caudal regression syndrome congenital malformation syringomyelia vertebral agenesis |
| title | A rare congenital malformation: caudal regression syndrome |
| title_full | A rare congenital malformation: caudal regression syndrome |
| title_fullStr | A rare congenital malformation: caudal regression syndrome |
| title_full_unstemmed | A rare congenital malformation: caudal regression syndrome |
| title_short | A rare congenital malformation: caudal regression syndrome |
| title_sort | rare congenital malformation caudal regression syndrome |
| topic | caudal regression syndrome congenital malformation syringomyelia vertebral agenesis |
| url |
https://www.panafrican-med-journal.com/content/article/14/30/pdf/30.pdf
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