Long-Term Simulation of Microgravity Induces Changes in Gene Expression in Breast Cancer Cells

Long-Term Simulation of Microgravity Induces Changes in Gene Expression in Breast Cancer Cells

Microgravity changes the gene expression pattern in various cell types. This study focuses on the breast cancer cell lines MCF-7 (less invasive) and MDA-MB-231 (triple-negative, highly invasive). The cells were cultured for 14 days under simulated microgravity (s-µ<i>g</i>) conditions us...

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Bibliographic Details
Main Authors: Jayashree Sahana, José Luis Cortés-Sánchez, Viviann Sandt, Daniela Melnik, Thomas J. Corydon, Herbert Schulz, Zexi Cai, Katja Evert, Daniela Grimm, Markus Wehland
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:International Journal of Molecular Sciences
Subjects:
breast cancer
spheroids
cytoskeleton
extracellular matrix
focal adhesion
microgravity
Online Access:https://www.mdpi.com/1422-0067/24/2/1181

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