Comparison of Substance Sources in Experimental Antimicrobial Susceptibility Testing
Funding is often a constraint when planning research, especially in countries where basic research is underfunded. Researchers must take into account these limitations, e.g., in relation to the selection of appropriate reagents, the source of which may affect the study’s final results. The aim of th...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-02-01
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| Series: | Scientia Pharmaceutica |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2218-0532/91/1/10 |
| _version_ | 1797609161169567744 |
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| author | Filip Bielec Małgorzata Brauncajs Dorota Pastuszak-Lewandoska |
| author_facet | Filip Bielec Małgorzata Brauncajs Dorota Pastuszak-Lewandoska |
| author_sort | Filip Bielec |
| collection | DOAJ |
| description | Funding is often a constraint when planning research, especially in countries where basic research is underfunded. Researchers must take into account these limitations, e.g., in relation to the selection of appropriate reagents, the source of which may affect the study’s final results. The aim of this article was to compare the results of bacteria susceptibility testing using three different sources of antimicrobial: the pure powder available from the supplier and two tablet formulations with different excipients. The chosen substance was furazidin (nitrofuran derivative). The susceptibility was tested on a group of 45 uropathogenic Enterobacterales using both microdilution and disk diffusion methods. The obtained results indicated that despite the relatively higher price, the powder appeared to be the best substance for scientific purposes, especially for quantitative determinations. |
| first_indexed | 2024-03-11T05:57:40Z |
| format | Article |
| id | doaj.art-d7311430d2034a4e8b0e1bf42cd2ad1e |
| institution | Directory Open Access Journal |
| issn | 0036-8709 2218-0532 |
| language | English |
| last_indexed | 2024-03-11T05:57:40Z |
| publishDate | 2023-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Scientia Pharmaceutica |
| spelling | doaj.art-d7311430d2034a4e8b0e1bf42cd2ad1e2023-11-17T13:42:29ZengMDPI AGScientia Pharmaceutica0036-87092218-05322023-02-019111010.3390/scipharm91010010Comparison of Substance Sources in Experimental Antimicrobial Susceptibility TestingFilip Bielec0Małgorzata Brauncajs1Dorota Pastuszak-Lewandoska2Department of Microbiology and Laboratory Medical Immunology, Medical University of Lodz, 90-151 Lodz, PolandDepartment of Microbiology and Laboratory Medical Immunology, Medical University of Lodz, 90-151 Lodz, PolandDepartment of Microbiology and Laboratory Medical Immunology, Medical University of Lodz, 90-151 Lodz, PolandFunding is often a constraint when planning research, especially in countries where basic research is underfunded. Researchers must take into account these limitations, e.g., in relation to the selection of appropriate reagents, the source of which may affect the study’s final results. The aim of this article was to compare the results of bacteria susceptibility testing using three different sources of antimicrobial: the pure powder available from the supplier and two tablet formulations with different excipients. The chosen substance was furazidin (nitrofuran derivative). The susceptibility was tested on a group of 45 uropathogenic Enterobacterales using both microdilution and disk diffusion methods. The obtained results indicated that despite the relatively higher price, the powder appeared to be the best substance for scientific purposes, especially for quantitative determinations.https://www.mdpi.com/2218-0532/91/1/10antimicrobial susceptibility testingmicrodilution susceptibility testdisk diffusion susceptibility testfurazidinEnterobacterales |
| spellingShingle | Filip Bielec Małgorzata Brauncajs Dorota Pastuszak-Lewandoska Comparison of Substance Sources in Experimental Antimicrobial Susceptibility Testing Scientia Pharmaceutica antimicrobial susceptibility testing microdilution susceptibility test disk diffusion susceptibility test furazidin Enterobacterales |
| title | Comparison of Substance Sources in Experimental Antimicrobial Susceptibility Testing |
| title_full | Comparison of Substance Sources in Experimental Antimicrobial Susceptibility Testing |
| title_fullStr | Comparison of Substance Sources in Experimental Antimicrobial Susceptibility Testing |
| title_full_unstemmed | Comparison of Substance Sources in Experimental Antimicrobial Susceptibility Testing |
| title_short | Comparison of Substance Sources in Experimental Antimicrobial Susceptibility Testing |
| title_sort | comparison of substance sources in experimental antimicrobial susceptibility testing |
| topic | antimicrobial susceptibility testing microdilution susceptibility test disk diffusion susceptibility test furazidin Enterobacterales |
| url | https://www.mdpi.com/2218-0532/91/1/10 |
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