Adenosine A<sub>2A</sub> Receptor Activation Regulates Niemann–Pick C1 Expression and Localization in Macrophages

Adenosine A<sub>2A</sub> Receptor Activation Regulates Niemann–Pick C1 Expression and Localization in Macrophages

Adenosine plays an important role in modulating immune cell function, particularly T cells and myeloid cells, such as macrophages and dendritic cells. Cell surface adenosine A<sub>2A</sub> receptors (A<sub>2A</sub>R) regulate the production of pro-inflammatory cytokines and c...

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Bibliographic Details
Main Authors: Adrienn Skopál, Gyula Ujlaki, Attila Tibor Gerencsér, Csaba Bankó, Zsolt Bacsó, Francisco Ciruela, László Virág, György Haskó, Endre Kókai
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Current Issues in Molecular Biology
Subjects:
adenosine receptor
Niemann–Pick C1 protein
lysosome-associated membrane protein 2
protein interaction
macrophage
Online Access:https://www.mdpi.com/1467-3045/45/6/315

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