Fibrotic Remodeling during Persistent Atrial Fibrillation: In Silico Investigation of the Role of Calcium for Human Atrial Myofibroblast Electrophysiology
During atrial fibrillation, cardiac tissue undergoes different remodeling processes at different scales from the molecular level to the tissue level. One central player that contributes to both electrical and structural remodeling is the myofibroblast. Based on recent experimental evidence on myofib...
Main Authors: | Jorge Sánchez, Beatriz Trenor, Javier Saiz, Olaf Dössel, Axel Loewe |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-10-01
|
Series: | Cells |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4409/10/11/2852 |
Similar Items
-
Editorial: Molecular, structural and electrophysiological remodeling in atrial fibrillation
by: Diego Franco, et al.
Published: (2023-10-01) -
Using Machine Learning to Characterize Atrial Fibrotic Substrate From Intracardiac Signals With a Hybrid in silico and in vivo Dataset
by: Jorge Sánchez, et al.
Published: (2021-07-01) -
Commentary: Virtual In-Silico Modeling Guided Catheter Ablation Predicts Effective Linear Ablation Lesion Set for Longstanding Persistent Atrial Fibrillation: Multicenter Prospective Randomized Study
by: Axel Loewe, et al.
Published: (2017-12-01) -
Heterogeneous Effects of Fibroblast-Myocyte Coupling in Different Regions of the Human Atria Under Conditions of Atrial Fibrillation
by: Jorge Sánchez, et al.
Published: (2019-07-01) -
Structural and electrophysiological determinants of atrial cardiomyopathy identify remodeling discrepancies between paroxysmal and persistent atrial fibrillation
by: Taiyuan Huang, et al.
Published: (2023-01-01)